Interictal EEG findings in two cases with 'double cortex' syndrome

Antonia Parmeggiani, Margherita Santucci, Paolo Ambrosetto, Alessandra Amadi, Elisabetta Baioni, Paola Giovanardi Rossi

Research output: Contribution to journalArticle

Abstract

'Double cortex' is a neuroblast migrational disorder characterized by a diffuse band of heterotopic grey matter between the lateral ventricles and cerebral cortex which may be normal or macrogyric. The authors report two girls with 'double cortex' syndrome presenting intractable partial epilepsy and severe mental retardation. EEG data are analysed in detail because such patients presented a particular interictal EEG background activity, not only with very stable features during the different stages of vigilance, but also uninfluenced by seizure frequency or duration. The authors raise the possibility that a further in vivo diagnostic parameter for this syndrome has been identified.

Original languageEnglish
Pages (from-to)320-324
Number of pages5
JournalBrain and Development
Volume16
Issue number4
DOIs
Publication statusPublished - 1994

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Keywords

  • Diffuse subcortical heterotopia
  • Double cortex
  • Drop seizure
  • EEG abnormality
  • EEG background activity
  • Intractable epilepsy
  • Mental retardation
  • Neuroblast migrational disorder
  • Partial epilepsy

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neurology

Cite this

Parmeggiani, A., Santucci, M., Ambrosetto, P., Amadi, A., Baioni, E., & Rossi, P. G. (1994). Interictal EEG findings in two cases with 'double cortex' syndrome. Brain and Development, 16(4), 320-324. https://doi.org/10.1016/0387-7604(94)90031-0