Interleukin-2 and interferon α 2 combination

Ineffectiveness of a single six-week course in patients with metastatic renal cancer pretreated with interferon alone

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Abstract

We have studied activity and toxicity of subcutaneous recombinant interleukin-2 and interferon α 2b in a series of 14 patients with advanced renal cell carcinoma. No objective response was observed, and the median survival was 16 months (range 3-19); toxicity was acceptable. All the patients had poor prognostic factors and were pretreated with interferon.

Original languageEnglish
Pages (from-to)1137-1139
Number of pages3
JournalOncology Reports
Volume3
Issue number6
Publication statusPublished - 1996

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Kidney Neoplasms
Interferons
Interleukin-2
Renal Cell Carcinoma
Survival

Keywords

  • interferon α
  • interleukin-2
  • renal cancer

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

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title = "Interleukin-2 and interferon α 2 combination: Ineffectiveness of a single six-week course in patients with metastatic renal cancer pretreated with interferon alone",
abstract = "We have studied activity and toxicity of subcutaneous recombinant interleukin-2 and interferon α 2b in a series of 14 patients with advanced renal cell carcinoma. No objective response was observed, and the median survival was 16 months (range 3-19); toxicity was acceptable. All the patients had poor prognostic factors and were pretreated with interferon.",
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AB - We have studied activity and toxicity of subcutaneous recombinant interleukin-2 and interferon α 2b in a series of 14 patients with advanced renal cell carcinoma. No objective response was observed, and the median survival was 16 months (range 3-19); toxicity was acceptable. All the patients had poor prognostic factors and were pretreated with interferon.

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