INTERLEUCHINA-2: CARATTERISTICHE BIOLOGICHE E POTENZIALITA TERAPEUTICHE IN ONCOLOGIA

Translated title of the contribution: Interleukin-2: Biological characteristics and therapeutic potential in oncology

L. Addabbo, A. Casamassima, M. Guida, I. Abbate, M. Correale, A. Latorre, A. Mastria, V. Lorusso, M. De Lena

Research output: Contribution to journalArticlepeer-review

Abstract

Immunotherapy with rIL-2 currently represents one of the most interesting therapeutic approaches to tumors. Ten patients with advanced phase neoplasms (3 melanomas and 7 renal) were admitted to the study. The subcutaneous treatment regime with rIL-2 (Proleukin-Cetus). The aim of the study is to monitor the peripheral immunological modifications induced by rIL-2 treatments and to detect eventual parameters correlated with clinical response. Preliminary analysis of our data demonstrate: subcutaneous administration of rIL-2 is able to induce an important immunological stimulation in all patients treated; nevertheless there seems not to be correlation between immunological parameters considered and the patients clinical response.

Translated title of the contributionInterleukin-2: Biological characteristics and therapeutic potential in oncology
Original languageItalian
Pages (from-to)21-26
Number of pages6
JournalFolia Oncologica
Volume15
Issue number1
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Oncology

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