Interleukin-22: Biomarker of maternal and fetal inflammation?

Iliana Bersani, Maria Pia De Carolis, Dirk Foell, Toni Weinhage, Esther Diana Rossi, Sara De Carolis, Serena Antonia Rubortone, Costantino Romagnoli, Christian Paul Speer

Research output: Contribution to journalArticlepeer-review


Histologic chorioamnionitis (HCA) is an intrauterine status of inflammation which may lead to the fetal inflammatory response syndrome. Inflammation is a pathogenetic mechanism also of preeclampsia, although not of microbial origin. The aim of the present pilot study was to evaluate the pattern of inflammatory cytokines in mothers and high-risk preterm infants during the perinatal period. Concentrations of proinflammatory and anti-inflammatory cytokines and C-reactive protein were evaluated in maternal, cord, and neonatal blood of very preterm infants

Original languageEnglish
Pages (from-to)4-10
Number of pages7
JournalImmunologic Research
Issue number1-2
Publication statusPublished - 2014


  • Chorioamnionitis
  • Cord blood
  • Interleukin 22
  • Placenta
  • Preeclampsia

ASJC Scopus subject areas

  • Immunology
  • Medicine(all)


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