Internal target volume defined by contrast-enhanced 4D-CT scan in unresectable pancreatic tumour: Evaluation and reproducibility

Giovanni Mauro Cattaneo, Paolo Passoni, Giulia Sangalli, Najla Slim, Barbara Longobardi, Pietro Mancosu, Valentino Bettinardi, Nadia Di Muzio, Riccardo Calandrino

Research output: Contribution to journalArticle


We compared customized ITVs obtained with CE-4D-CT imaging (ITV 4D) with a population-based (ITV PBC) in 29 patients (PTs) and evaluated the intra-observer ITV delineation reproducibility in 5 PTs with unresectable pancreatic ductal adenocarcinoma (PDA). The ITV PBC was quite different from the ITV 4D, with under/over estimation of volume. Intra-observer volume delineation variability on CE-4D-CT and on a single-phase CE-CT were similar (27.6% vs 24.9%).

Original languageEnglish
Pages (from-to)525-529
Number of pages5
JournalRadiotherapy and Oncology
Issue number3
Publication statusPublished - Dec 2010



  • Internal target volume
  • Intra-observer variability
  • Pancreatic ductal adenocarcinoma
  • Radiotherapy
  • Respiratory-gated 4D-CT

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Hematology

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