International expert panel on the use of primary (preoperative) systemic treatment of operable breast cancer: Review and recommendations

Manfred Kaufmann, Gunter Von Minckwitz, Roy Smith, Vicente Valero, Luca Gianni, Wolfgang Eiermann, Anthony Howell, Serban Dan Costa, Philippe Beuzeboc, Michael Untch, Jens Uwe Blohmer, Hans Peter Sinn, Rolf Sittek, Rainer Souchon, Augustinos H. Tulusan, Tanja Volm, Hans Jörg Senn

Research output: Contribution to journalArticle

Abstract

Primary systemic therapy (PST) represents the standard of care in patients with locally advanced breast cancer. In addition, there is increasing information on PST in operable breast disease that supports the use of PST in routine practice. However, current regimens and techniques vary. To address this concern, a group of representatives from breast cancer clinical research groups in France, Germany, Italy, the United Kingdom, and the United States reviewed all available data on prospective randomized trials in this setting. Recommendations are made regarding terminology, indications, regimen, diagnosis before treatment, monitoring of efficacy, tumor localization, surgery, pathologic evaluation, and postoperative treatment.

Original languageEnglish
Pages (from-to)2600-2608
Number of pages9
JournalJournal of Clinical Oncology
Volume21
Issue number13
DOIs
Publication statusPublished - Jul 1 2003

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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    Kaufmann, M., Von Minckwitz, G., Smith, R., Valero, V., Gianni, L., Eiermann, W., Howell, A., Dan Costa, S., Beuzeboc, P., Untch, M., Blohmer, J. U., Sinn, H. P., Sittek, R., Souchon, R., Tulusan, A. H., Volm, T., & Senn, H. J. (2003). International expert panel on the use of primary (preoperative) systemic treatment of operable breast cancer: Review and recommendations. Journal of Clinical Oncology, 21(13), 2600-2608. https://doi.org/10.1200/JCO.2003.01.136