TY - JOUR
T1 - Interplay between mitral regurgitation and transcatheter aortic valve replacement with the corevalve revalving system
T2 - A multicenter registry
AU - Bedogni, Francesco
AU - Latib, Azeem
AU - De Marco, Federico
AU - Agnifili, Mauro
AU - Oreglia, Jacopo
AU - Pizzocri, Samuele
AU - Latini, Roberto A.
AU - Lanotte, Stefania
AU - Petronio, Anna Sonia
AU - De Carlo, Marco
AU - Ettori, Federica
AU - Fiorina, Claudia
AU - Poli, Arnaldo
AU - Cirri, Silvia
AU - De Servi, Stefano
AU - Ramondo, Angelo
AU - Tarantini, Giuseppe
AU - Marzocchi, Antonio
AU - Fiorilli, Rosario
AU - Klugmann, Silvio
AU - Ussia, Gian Paolo
AU - Tamburino, Corrado
AU - Maisano, Francesco
AU - Brambilla, Nedy
AU - Colombo, Antonio
AU - Testa, Luca
PY - 2013/11/5
Y1 - 2013/11/5
N2 - BACKGROUND - : Little is known of the prognostic significance of mitral regurgitation (MR) on transcatheter aortic valve replacement (TAVR), the impact of TAVR on MR severity, and the variables associated with possible post-TAVR improvement in MR. We evaluated these issues in a multicenter registry of patients undergoing CoreValve Revalving System-TAVR. METHODS AND RESULTS - : Among 1007 consecutive patients, 670 (66.5%), 243 (24.1%), and 94 (9.3%) presented with no/mild, moderate, and severe MR, respectively. At 1 month after TAVR, patients with severe or moderate MR showed comparable mortality rates (odds ratio, 1.1; 95% confidence interval [95% CI], 0.7-1.55; P=0.2), but both were significantly higher compared with patients with mild/no MR (odds ratio, 2.2; 95% CI, 1.78-3.28; P
AB - BACKGROUND - : Little is known of the prognostic significance of mitral regurgitation (MR) on transcatheter aortic valve replacement (TAVR), the impact of TAVR on MR severity, and the variables associated with possible post-TAVR improvement in MR. We evaluated these issues in a multicenter registry of patients undergoing CoreValve Revalving System-TAVR. METHODS AND RESULTS - : Among 1007 consecutive patients, 670 (66.5%), 243 (24.1%), and 94 (9.3%) presented with no/mild, moderate, and severe MR, respectively. At 1 month after TAVR, patients with severe or moderate MR showed comparable mortality rates (odds ratio, 1.1; 95% confidence interval [95% CI], 0.7-1.55; P=0.2), but both were significantly higher compared with patients with mild/no MR (odds ratio, 2.2; 95% CI, 1.78-3.28; P
KW - aortic valve
KW - aortic valve stenosis
KW - mitral valve insufficiency
UR - http://www.scopus.com/inward/record.url?scp=84887209841&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84887209841&partnerID=8YFLogxK
U2 - 10.1161/CIRCULATIONAHA.113.001822
DO - 10.1161/CIRCULATIONAHA.113.001822
M3 - Article
C2 - 24088530
AN - SCOPUS:84887209841
VL - 128
SP - 2145
EP - 2153
JO - Circulation
JF - Circulation
SN - 0009-7322
IS - 19
ER -