Interscalene brachial plexus anaesthesia with 0.5%, 0.75% or 1% ropivacaine: A double-blind comparison with 2% mepivacaine

A. Casati, G. Fanelli, G. Aldegheri, M. Berti, E. Colnaghi, V. Cedrati, G. Torri

Research output: Contribution to journalArticle

Abstract

We have compared interscalene brachial plexus block performed with ropivacaine or mepivacaine in 60 healthy patients undergoing elective shoulder surgery. Patients were allocated randomly to receive interscalene brachial plexus anaesthesia with 20 ml of 0.5% ropivacaine (n = 15), 0.75% ropivacaine (n = 15), 1% ropivacaine (n = 15) or 2% mepivacaine (n = 15). Readiness for surgery (loss of pinprick sensation from C4 to C7 and inability to elevate the limb from the bed) was achieved sooner with 1% ropivacaine (mean 10 (SD 5) min) than with 0.5% ropivacaine (22 (7) min) (P <0.001) or 2% mepivacaine (18 (9) min) (P <0.02). Postoperative analgesia was similar with the three ropivacaine concentrations (11.5 (5) h, 10.7 (2) h and 10 (2.4) h with 0.5%, 0.75% and 1% concentrations, respectively) and nearly two-fold longer compared with 2% mepivacaine (5.1 (2.7) h) (P <0.001).

Original languageEnglish
Pages (from-to)872-875
Number of pages4
JournalBritish Journal of Anaesthesia
Volume83
Issue number6
Publication statusPublished - Dec 1999

Keywords

  • Anaesthetic techniques, regional, brachial plexus
  • Anaesthetics local, mepivacaine
  • Anaesthetics local, ropivacaine

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Fingerprint Dive into the research topics of 'Interscalene brachial plexus anaesthesia with 0.5%, 0.75% or 1% ropivacaine: A double-blind comparison with 2% mepivacaine'. Together they form a unique fingerprint.

  • Cite this

    Casati, A., Fanelli, G., Aldegheri, G., Berti, M., Colnaghi, E., Cedrati, V., & Torri, G. (1999). Interscalene brachial plexus anaesthesia with 0.5%, 0.75% or 1% ropivacaine: A double-blind comparison with 2% mepivacaine. British Journal of Anaesthesia, 83(6), 872-875.