TY - JOUR
T1 - Interscalene brachial plexus anaesthesia with 0.5%, 0.75% or 1% ropivacaine
T2 - A double-blind comparison with 2% mepivacaine
AU - Casati, A.
AU - Fanelli, G.
AU - Aldegheri, G.
AU - Berti, M.
AU - Colnaghi, E.
AU - Cedrati, V.
AU - Torri, G.
PY - 1999/12
Y1 - 1999/12
N2 - We have compared interscalene brachial plexus block performed with ropivacaine or mepivacaine in 60 healthy patients undergoing elective shoulder surgery. Patients were allocated randomly to receive interscalene brachial plexus anaesthesia with 20 ml of 0.5% ropivacaine (n = 15), 0.75% ropivacaine (n = 15), 1% ropivacaine (n = 15) or 2% mepivacaine (n = 15). Readiness for surgery (loss of pinprick sensation from C4 to C7 and inability to elevate the limb from the bed) was achieved sooner with 1% ropivacaine (mean 10 (SD 5) min) than with 0.5% ropivacaine (22 (7) min) (P <0.001) or 2% mepivacaine (18 (9) min) (P <0.02). Postoperative analgesia was similar with the three ropivacaine concentrations (11.5 (5) h, 10.7 (2) h and 10 (2.4) h with 0.5%, 0.75% and 1% concentrations, respectively) and nearly two-fold longer compared with 2% mepivacaine (5.1 (2.7) h) (P <0.001).
AB - We have compared interscalene brachial plexus block performed with ropivacaine or mepivacaine in 60 healthy patients undergoing elective shoulder surgery. Patients were allocated randomly to receive interscalene brachial plexus anaesthesia with 20 ml of 0.5% ropivacaine (n = 15), 0.75% ropivacaine (n = 15), 1% ropivacaine (n = 15) or 2% mepivacaine (n = 15). Readiness for surgery (loss of pinprick sensation from C4 to C7 and inability to elevate the limb from the bed) was achieved sooner with 1% ropivacaine (mean 10 (SD 5) min) than with 0.5% ropivacaine (22 (7) min) (P <0.001) or 2% mepivacaine (18 (9) min) (P <0.02). Postoperative analgesia was similar with the three ropivacaine concentrations (11.5 (5) h, 10.7 (2) h and 10 (2.4) h with 0.5%, 0.75% and 1% concentrations, respectively) and nearly two-fold longer compared with 2% mepivacaine (5.1 (2.7) h) (P <0.001).
KW - Anaesthetic techniques, regional, brachial plexus
KW - Anaesthetics local, mepivacaine
KW - Anaesthetics local, ropivacaine
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M3 - Article
C2 - 10700785
AN - SCOPUS:0032721337
VL - 83
SP - 872
EP - 875
JO - British Journal of Anaesthesia
JF - British Journal of Anaesthesia
SN - 0007-0912
IS - 6
ER -