TY - JOUR
T1 - Interstitial cystitis is associated with vulvodynia and sexual dysfunction-A case-control study
AU - Gardella, Barbara
AU - Porru, Daniele
AU - Nappi, Rossella E.
AU - Daccò, Maria Diletta
AU - Chiesa, Alessia
AU - Spinillo, Arsenio
PY - 2011/6
Y1 - 2011/6
N2 - Introduction. Dyspareunia and sexual dysfunction are common in women with urological disorders. The study of comorbidity between interstitial cystitis (IC) and vulvodynia seems to be relevant to understand the mechanism generating pain in these conditions. Aim. To conduct a case-control study for evaluating vulvodynia and sexual dysfunction in women with IC. Methods. Forty-seven women with new diagnosis (National Institutes of Health [NIH]/National Institute of Diabetes and Digestive and Kidney Diseases [NIDDK] Criteria) of IC were compared with 188 age-matched, negative controls. Each woman completed a semi-structured interview and the Female Sexual Function Index (FSFI). A gynecological examination to assess vulvodynia (cotton swab testing) and genital health (vulvoscopy, Pap smear, culture, and vaginal health index score [VHIS]) was performed. Main Outcome Measures. Prevalence of vulvodynia, sexual function, and sociodemographic/gynecological variables significantly associated with IC. Results. Spontaneous or provoked vulvodynia was reported by 23.4% and 74.5% of IC cases, respectively. Sexual function was significantly impaired (median total FSFI score: IC cases 16.85±8.73 vs. controls 27.34±6.41; P2 for trend=38.2, P
AB - Introduction. Dyspareunia and sexual dysfunction are common in women with urological disorders. The study of comorbidity between interstitial cystitis (IC) and vulvodynia seems to be relevant to understand the mechanism generating pain in these conditions. Aim. To conduct a case-control study for evaluating vulvodynia and sexual dysfunction in women with IC. Methods. Forty-seven women with new diagnosis (National Institutes of Health [NIH]/National Institute of Diabetes and Digestive and Kidney Diseases [NIDDK] Criteria) of IC were compared with 188 age-matched, negative controls. Each woman completed a semi-structured interview and the Female Sexual Function Index (FSFI). A gynecological examination to assess vulvodynia (cotton swab testing) and genital health (vulvoscopy, Pap smear, culture, and vaginal health index score [VHIS]) was performed. Main Outcome Measures. Prevalence of vulvodynia, sexual function, and sociodemographic/gynecological variables significantly associated with IC. Results. Spontaneous or provoked vulvodynia was reported by 23.4% and 74.5% of IC cases, respectively. Sexual function was significantly impaired (median total FSFI score: IC cases 16.85±8.73 vs. controls 27.34±6.41; P2 for trend=38.2, P
KW - Bladder and Vulvar Pain
KW - Interstitial Cystitis
KW - Menopause
KW - Oral Contraceptives
KW - Sexual Pain
KW - Vulvodynia
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U2 - 10.1111/j.1743-6109.2011.02251.x
DO - 10.1111/j.1743-6109.2011.02251.x
M3 - Article
C2 - 21477020
AN - SCOPUS:79957881473
VL - 8
SP - 1726
EP - 1734
JO - Journal of Sexual Medicine
JF - Journal of Sexual Medicine
SN - 1743-6095
IS - 6
ER -