Fotocoagulazione interstiziale laser dei tumori del fegato

Translated title of the contribution: Interstitial laser photocoagulation in liver tumors

B. Caspani, P. Cecconi, P. D. Vigna

Research output: Contribution to journalArticlepeer-review


Background and aim of the work: Interstitial Laser Photocoagulation (ILP) is a recently suggested method to ablate solid tumors by an interstitial approach. In this pilot clinical study we present our experience in treating neoplastic lesions of the liver. Methods: 44 lesions were treated in 23 patients, 7 suffering from HCC, 16 from hepatic metastases. The diameter of the lesions ranged from 10 to 65 mm. ILP was performed by a Nd-YAG Laser with optical fibres 0.8 mm in diameter via 18G needles positioned with US and/or CT guidance. With power ranging from 5 to 10W, the energy required in each treatment was 800-1.000 Joule. The extent of the tumour necrosis was evaluated with non-contrast and contrast-enhanced CT at 48 hours, 2 weeks and every 2 months. Results: Complete necrosis of neoplastic tissue was related to decrease in volume of the lesion and lacking the enhancement at CT. Among the 35 lesions with a follow-up of at least 2 months, 26 (74.3%) have shown at contrast-enhanced CT complete necrosis, 9 (25.7%) incomplete necrosis. There were no major complications. Conclusion: ILP is effective for tissue destruction of liver tumors. The therapy is reproducible, easily performed and minimally invasive.

Translated title of the contributionInterstitial laser photocoagulation in liver tumors
Original languageItalian
Pages (from-to)99-105
Number of pages7
Issue number2
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Internal Medicine


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