Fotocoagulazione interstiziale con luce laser dei tumori del fegato

Translated title of the contribution: Interstitial Laser photocoagulation of liver cancers

Bruno Caspani, Pietro Cecconi, Riccardo Bottelli, Paolo Della Vigna, Gaetano Ideo, Gino Gozzi

Research output: Contribution to journalArticlepeer-review


Introduction. Interstitial Laser photocoagulation (ILP) is a recent interventional procedure performed under US or CT guidance which is capable of inducing thermal necrosis in solid tumors. We have used this technique for about 2 years to treat primary and secondary liver cancers. Materials and methods. Thirty-five patients, 20 of them with liver metastases and 15 with HCC, have been examined; 59 lesions in all, ranging in diameter 10 to 65 mm. Forty-nine lesions have been followed-up for at least 2 months and 25 for at least 6 months. The treatment was performed positioning one to six (18-21 G) modified Chiba needles in the lesions to be treated, according to their sizes, under US or CT guidance. The optical fibers (400-800 μ) were then inserted and the Laser was fired to administer 1000 Joule/session, with 5-10 W power range. The US and CT patterns of the ILP-treated lesions are reported. Results. Dynamic CT examinations 2 months after treatment showed complete tumor destruction in 77.5% of the lesions. The best results were obtained in the lesions <3 cm Ø; in particular, 32/38 lesions (84.2%) <3 cm and with at least 2 months' follow-up exhibited complete necrosis, as did 6 of 11 lesions (54.6%) over 3 cm Ø. When residual tumor tissue was demonstrated, further ILP sessions were useless. We observed only few complications which resolved spontaneously in all cases. Conclusions. At present, ILP remains an experimental procedure: further studies on larger series of patients and comparison with the results of other interventional procedures are needed to confirm its efficacy in treating primary and secondary liver cancers.

Translated title of the contributionInterstitial Laser photocoagulation of liver cancers
Original languageItalian
Pages (from-to)346-354
Number of pages9
JournalRadiologia Medica
Issue number4
Publication statusPublished - Oct 1997

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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