I carcinomi di intervallo quali indicatori di performance di un programma di screening

Translated title of the contribution: Interval cancers as indicators of performance in screening programmes

Stefano Ciatto, Carlo Naldoni, Antonio Ponti, Livia Giordano, Daniela Giorgi, Alfonso Frigerio, Marcello Vettorazzi, Lauro Bucchi, Luigi Bisanti, Marco Petrella, Eugenio Paci, Gianni Saguatti, Dolores Santini, Marco Rosselli Del Turco, Marco Zappa, Paolo Giorgi Rossi, Vittorio Corsetti, Luisella Milanesio, Priscilla Sassoli De'Bianchi

Research output: Contribution to journalArticlepeer-review


GISMa analyses the interval cancer (IS) topic providing guidelines and reference standards in addition to CE recommendations. IC identification is based on Cancer Registries (CR), if existing, or on hospital discharge records, in alternative. The optimal measure of IC frequency (inversely correlated with sensitivity) is the IC proportional incidence (observed IC I carcinomas expected in absence of screening). Otherformulas (ICIIC + screen detected cancers; IC rate per 1,000 negative screens) look less reliable. IC stage at diagnosis (if available through CR) must be compared with screen detected cancer and cancer detected in non-attenders. Review of mammograms preceding the IC (coded as screening error, minimal signs, or occult) should be done mainly with a blind procedure (IC mixed with negative controls), as this procedure is more representative ofthe original scenario and more respectful of radiologist's rights.

Translated title of the contributionInterval cancers as indicators of performance in screening programmes
Original languageItalian
Pages (from-to)93-98
Number of pages6
JournalEpidemiologia e prevenzione
Issue number2
Publication statusPublished - Mar 2008

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health


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