Interventional oncology in the elderly: Complications and early response in liver and kidney malignancies

L. Monfardini, P. Della Vigna, G. Bonomo, F. Orsi, M. Tullii, D. Disalvatore, S. Monfardini

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objectives: The complication rate, loco-regional responses and length of hospital stay were analyzed in patients with liver and kidney cancer older than 70. years treated with interventional oncology procedures. The findings from the older population were compared with the younger patients (<70 years) to detect any difference not related to chance. Materials and methods: Prospectively collected data on patients who underwent hepatic artery embolization (with or without radiofrequency ablation) and kidney radiofrequency ablation were retrospectively analyzed. Complication rates, loco-regional responses and length of hospital stay for patients older and younger than 70 were compared. Results: 163 patients were treated, 66 (40.5%) older and 97 (59.5%) younger than 70. years. The complication rate in patients older than 70 was 4.5% (3/66 pts) versus 3.1% (3/97 pts) (p = 0.69) in the younger age-group. The complication rates for the liver embolization group, liver embolization plus radiofrequency and kidney radiofrequency group were 2/90 pts (2.2%), 2/42 pts (4.8%) and 2/31 pts (6.5%), respectively (p = 0.46). Median hospital stay was three nights in both older and younger patients. Response rates were not significantly influenced by age. Conclusion: Liver embolization with or without radiofrequency and renal radiofrequency are safe and effective in older patients. Age alone should not be considered a contraindication to treatment in carefully selected patients.

Original languageEnglish
Pages (from-to)58-63
Number of pages6
JournalJournal of Geriatric Oncology
Volume4
Issue number1
DOIs
Publication statusPublished - Jan 2013

Fingerprint

Kidney
Liver
Length of Stay
Neoplasms
Kidney Neoplasms
Hepatic Artery
Liver Neoplasms
Age Groups
Population

Keywords

  • Bland arterial embolization
  • Elderly
  • Interventional oncology
  • Radiofrequency ablation

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Oncology

Cite this

Interventional oncology in the elderly : Complications and early response in liver and kidney malignancies. / Monfardini, L.; Della Vigna, P.; Bonomo, G.; Orsi, F.; Tullii, M.; Disalvatore, D.; Monfardini, S.

In: Journal of Geriatric Oncology, Vol. 4, No. 1, 01.2013, p. 58-63.

Research output: Contribution to journalArticle

@article{953d7f3508204cbeb3838afe08e349e8,
title = "Interventional oncology in the elderly: Complications and early response in liver and kidney malignancies",
abstract = "Objectives: The complication rate, loco-regional responses and length of hospital stay were analyzed in patients with liver and kidney cancer older than 70. years treated with interventional oncology procedures. The findings from the older population were compared with the younger patients (<70 years) to detect any difference not related to chance. Materials and methods: Prospectively collected data on patients who underwent hepatic artery embolization (with or without radiofrequency ablation) and kidney radiofrequency ablation were retrospectively analyzed. Complication rates, loco-regional responses and length of hospital stay for patients older and younger than 70 were compared. Results: 163 patients were treated, 66 (40.5{\%}) older and 97 (59.5{\%}) younger than 70. years. The complication rate in patients older than 70 was 4.5{\%} (3/66 pts) versus 3.1{\%} (3/97 pts) (p = 0.69) in the younger age-group. The complication rates for the liver embolization group, liver embolization plus radiofrequency and kidney radiofrequency group were 2/90 pts (2.2{\%}), 2/42 pts (4.8{\%}) and 2/31 pts (6.5{\%}), respectively (p = 0.46). Median hospital stay was three nights in both older and younger patients. Response rates were not significantly influenced by age. Conclusion: Liver embolization with or without radiofrequency and renal radiofrequency are safe and effective in older patients. Age alone should not be considered a contraindication to treatment in carefully selected patients.",
keywords = "Bland arterial embolization, Elderly, Interventional oncology, Radiofrequency ablation",
author = "L. Monfardini and {Della Vigna}, P. and G. Bonomo and F. Orsi and M. Tullii and D. Disalvatore and S. Monfardini",
year = "2013",
month = "1",
doi = "10.1016/j.jgo.2012.09.001",
language = "English",
volume = "4",
pages = "58--63",
journal = "Journal of Geriatric Oncology",
issn = "1879-4068",
publisher = "Elsevier Limited",
number = "1",

}

TY - JOUR

T1 - Interventional oncology in the elderly

T2 - Complications and early response in liver and kidney malignancies

AU - Monfardini, L.

AU - Della Vigna, P.

AU - Bonomo, G.

AU - Orsi, F.

AU - Tullii, M.

AU - Disalvatore, D.

AU - Monfardini, S.

PY - 2013/1

Y1 - 2013/1

N2 - Objectives: The complication rate, loco-regional responses and length of hospital stay were analyzed in patients with liver and kidney cancer older than 70. years treated with interventional oncology procedures. The findings from the older population were compared with the younger patients (<70 years) to detect any difference not related to chance. Materials and methods: Prospectively collected data on patients who underwent hepatic artery embolization (with or without radiofrequency ablation) and kidney radiofrequency ablation were retrospectively analyzed. Complication rates, loco-regional responses and length of hospital stay for patients older and younger than 70 were compared. Results: 163 patients were treated, 66 (40.5%) older and 97 (59.5%) younger than 70. years. The complication rate in patients older than 70 was 4.5% (3/66 pts) versus 3.1% (3/97 pts) (p = 0.69) in the younger age-group. The complication rates for the liver embolization group, liver embolization plus radiofrequency and kidney radiofrequency group were 2/90 pts (2.2%), 2/42 pts (4.8%) and 2/31 pts (6.5%), respectively (p = 0.46). Median hospital stay was three nights in both older and younger patients. Response rates were not significantly influenced by age. Conclusion: Liver embolization with or without radiofrequency and renal radiofrequency are safe and effective in older patients. Age alone should not be considered a contraindication to treatment in carefully selected patients.

AB - Objectives: The complication rate, loco-regional responses and length of hospital stay were analyzed in patients with liver and kidney cancer older than 70. years treated with interventional oncology procedures. The findings from the older population were compared with the younger patients (<70 years) to detect any difference not related to chance. Materials and methods: Prospectively collected data on patients who underwent hepatic artery embolization (with or without radiofrequency ablation) and kidney radiofrequency ablation were retrospectively analyzed. Complication rates, loco-regional responses and length of hospital stay for patients older and younger than 70 were compared. Results: 163 patients were treated, 66 (40.5%) older and 97 (59.5%) younger than 70. years. The complication rate in patients older than 70 was 4.5% (3/66 pts) versus 3.1% (3/97 pts) (p = 0.69) in the younger age-group. The complication rates for the liver embolization group, liver embolization plus radiofrequency and kidney radiofrequency group were 2/90 pts (2.2%), 2/42 pts (4.8%) and 2/31 pts (6.5%), respectively (p = 0.46). Median hospital stay was three nights in both older and younger patients. Response rates were not significantly influenced by age. Conclusion: Liver embolization with or without radiofrequency and renal radiofrequency are safe and effective in older patients. Age alone should not be considered a contraindication to treatment in carefully selected patients.

KW - Bland arterial embolization

KW - Elderly

KW - Interventional oncology

KW - Radiofrequency ablation

UR - http://www.scopus.com/inward/record.url?scp=84872612693&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84872612693&partnerID=8YFLogxK

U2 - 10.1016/j.jgo.2012.09.001

DO - 10.1016/j.jgo.2012.09.001

M3 - Article

C2 - 24071493

AN - SCOPUS:84872612693

VL - 4

SP - 58

EP - 63

JO - Journal of Geriatric Oncology

JF - Journal of Geriatric Oncology

SN - 1879-4068

IS - 1

ER -