Interventional oncology in the elderly: Complications and early response in liver and kidney malignancies

L. Monfardini, P. Della Vigna, G. Bonomo, F. Orsi, M. Tullii, D. Disalvatore, S. Monfardini

Research output: Contribution to journalArticle

Abstract

Objectives: The complication rate, loco-regional responses and length of hospital stay were analyzed in patients with liver and kidney cancer older than 70. years treated with interventional oncology procedures. The findings from the older population were compared with the younger patients (<70 years) to detect any difference not related to chance. Materials and methods: Prospectively collected data on patients who underwent hepatic artery embolization (with or without radiofrequency ablation) and kidney radiofrequency ablation were retrospectively analyzed. Complication rates, loco-regional responses and length of hospital stay for patients older and younger than 70 were compared. Results: 163 patients were treated, 66 (40.5%) older and 97 (59.5%) younger than 70. years. The complication rate in patients older than 70 was 4.5% (3/66 pts) versus 3.1% (3/97 pts) (p = 0.69) in the younger age-group. The complication rates for the liver embolization group, liver embolization plus radiofrequency and kidney radiofrequency group were 2/90 pts (2.2%), 2/42 pts (4.8%) and 2/31 pts (6.5%), respectively (p = 0.46). Median hospital stay was three nights in both older and younger patients. Response rates were not significantly influenced by age. Conclusion: Liver embolization with or without radiofrequency and renal radiofrequency are safe and effective in older patients. Age alone should not be considered a contraindication to treatment in carefully selected patients.

Original languageEnglish
Pages (from-to)58-63
Number of pages6
JournalJournal of Geriatric Oncology
Volume4
Issue number1
DOIs
Publication statusPublished - Jan 2013

Keywords

  • Bland arterial embolization
  • Elderly
  • Interventional oncology
  • Radiofrequency ablation

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Oncology

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