TY - JOUR
T1 - Intra-abdominal pressure may be decreased non-invasively by continuous negative extra-abdominal pressure (NEXAP)
AU - Valenza, Franco
AU - Bottino, Nicola
AU - Canavesi, Katia
AU - Lissoni, Alfredo
AU - Alongi, Salvatore
AU - Losappio, Sabina
AU - Carlesso, Eleonora
AU - Gattinoni, Luciano
PY - 2003/11
Y1 - 2003/11
N2 - Objective: To investigate the possibility of artificially decreasing intra-abdominal pressure (IAP) by applying continuous negative pressure around the abdomen. Material and methods: We investigated the effects of negative extra-abdominal pressure (NEXAP) on IAP and central venous pressure (CVP) in 30 patients admitted to our intensive care unit (age 57±17 years, BMI 26.1±4.0 kg/m2, SAPS II 41.8± 17.0). Patients with severe hemodynamic instability and/or those admitted following a laparotomy were not studied. Measurements included bladder pressure as an estimate of IAP, CVP, invasive mean arterial pressure (MAP) and heart rate (HR). In five patients extensive hemodynamic measurements were also taken using a Swan-Ganz catheter. Following measurements at baseline (Basal), NEXAP (Life Care - Nev 100, Respironics) was applied on the abdomen, in random order, at a pressure equal to IAP (NEXAP0), 5 cmH2O (NEXAP-5) or 10 cmH2O (NEXAP-10) more negative than NEXAP0. Results: Basal IAP ranged from 4 to 22 mmHg. NEXAP decreased IAP from 8.7±4.3 mmHg to 6±4.2 (Basal vs NEXAP0 p2=0.778, p
AB - Objective: To investigate the possibility of artificially decreasing intra-abdominal pressure (IAP) by applying continuous negative pressure around the abdomen. Material and methods: We investigated the effects of negative extra-abdominal pressure (NEXAP) on IAP and central venous pressure (CVP) in 30 patients admitted to our intensive care unit (age 57±17 years, BMI 26.1±4.0 kg/m2, SAPS II 41.8± 17.0). Patients with severe hemodynamic instability and/or those admitted following a laparotomy were not studied. Measurements included bladder pressure as an estimate of IAP, CVP, invasive mean arterial pressure (MAP) and heart rate (HR). In five patients extensive hemodynamic measurements were also taken using a Swan-Ganz catheter. Following measurements at baseline (Basal), NEXAP (Life Care - Nev 100, Respironics) was applied on the abdomen, in random order, at a pressure equal to IAP (NEXAP0), 5 cmH2O (NEXAP-5) or 10 cmH2O (NEXAP-10) more negative than NEXAP0. Results: Basal IAP ranged from 4 to 22 mmHg. NEXAP decreased IAP from 8.7±4.3 mmHg to 6±4.2 (Basal vs NEXAP0 p2=0.778, p
KW - Abdominal compartment syndrome
KW - Intensive care
KW - Intra-abdominal pressure
KW - Negative extra-abdominal pressure
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U2 - 10.1007/s00134-003-2013-7
DO - 10.1007/s00134-003-2013-7
M3 - Article
C2 - 14530858
AN - SCOPUS:0344394205
VL - 29
SP - 2063
EP - 2067
JO - Intensive Care Medicine
JF - Intensive Care Medicine
SN - 0342-4642
IS - 11
ER -