Intra-abdominal pressure may be decreased non-invasively by continuous negative extra-abdominal pressure (NEXAP)

Franco Valenza, Nicola Bottino, Katia Canavesi, Alfredo Lissoni, Salvatore Alongi, Sabina Losappio, Eleonora Carlesso, Luciano Gattinoni

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To investigate the possibility of artificially decreasing intra-abdominal pressure (IAP) by applying continuous negative pressure around the abdomen. Material and methods: We investigated the effects of negative extra-abdominal pressure (NEXAP) on IAP and central venous pressure (CVP) in 30 patients admitted to our intensive care unit (age 57±17 years, BMI 26.1±4.0 kg/m2, SAPS II 41.8± 17.0). Patients with severe hemodynamic instability and/or those admitted following a laparotomy were not studied. Measurements included bladder pressure as an estimate of IAP, CVP, invasive mean arterial pressure (MAP) and heart rate (HR). In five patients extensive hemodynamic measurements were also taken using a Swan-Ganz catheter. Following measurements at baseline (Basal), NEXAP (Life Care - Nev 100, Respironics) was applied on the abdomen, in random order, at a pressure equal to IAP (NEXAP0), 5 cmH2O (NEXAP-5) or 10 cmH2O (NEXAP-10) more negative than NEXAP0. Results: Basal IAP ranged from 4 to 22 mmHg. NEXAP decreased IAP from 8.7±4.3 mmHg to 6±4.2 (Basal vs NEXAP0 p2=0.778, p

Original languageEnglish
Pages (from-to)2063-2067
Number of pages5
JournalIntensive Care Medicine
Volume29
Issue number11
DOIs
Publication statusPublished - Nov 2003

Keywords

  • Abdominal compartment syndrome
  • Intensive care
  • Intra-abdominal pressure
  • Negative extra-abdominal pressure

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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