Intra- and internerve cross-sectional area variability

New ultrasound measures

Luca Padua, Carlo Martinoli, Costanza Pazzaglia, Marta Lucchetta, Giuseppe Granata, Carmen Erra, Chiara Briani

Research output: Contribution to journalArticle

77 Citations (Scopus)

Abstract

Introduction: Nerve involvement in immune-related neuropathies is non-homogeneous, and therefore characterization of ultrasound (US) abnormalities is difficult. We developed two measures to quantify US abnormalities in immune-related neuropathies. Methods: Intranerve cross-sectional area (CSA) variability for each nerve was calculated as: maximal CSA/minimal CSA. Internerve CSA variability for each patient was calculated as: maximal intranerve CSA variability/minimal intranerve CSA variability. Six patients underwent US evaluation of the median, ulnar, and fibular nerves, and the abnormalities were scored with our newly developed measures. Results: The new measures were applicable to all nerves and patients. The highest degree of intra- and internerve CSA variability was observed in multifocal motor neuropathy, consistent with the asymmetric characteristics of this neuropathy. Conclusions: The application of intra- and internerve CSA variability measures allows us to quantify the heterogeneity of nerves and nerve segments and identify different US patterns in diverse immune-related neuropathies.

Original languageEnglish
Pages (from-to)730-733
Number of pages4
JournalMuscle and Nerve
Volume45
Issue number5
DOIs
Publication statusPublished - May 2012

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Peroneal Nerve
Ulnar Nerve
Median Nerve

Keywords

  • Cross-sectional area
  • Immune-related neuropathies
  • Ultrasound measures
  • Variability, diagnosis, outcome measures, nerve volume

ASJC Scopus subject areas

  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)
  • Physiology

Cite this

Intra- and internerve cross-sectional area variability : New ultrasound measures. / Padua, Luca; Martinoli, Carlo; Pazzaglia, Costanza; Lucchetta, Marta; Granata, Giuseppe; Erra, Carmen; Briani, Chiara.

In: Muscle and Nerve, Vol. 45, No. 5, 05.2012, p. 730-733.

Research output: Contribution to journalArticle

Padua, Luca ; Martinoli, Carlo ; Pazzaglia, Costanza ; Lucchetta, Marta ; Granata, Giuseppe ; Erra, Carmen ; Briani, Chiara. / Intra- and internerve cross-sectional area variability : New ultrasound measures. In: Muscle and Nerve. 2012 ; Vol. 45, No. 5. pp. 730-733.
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