Abstract
Purpose. To report our personal experience with the locoregional treatment of breast cancer. Material and methods. Eighteen patients aged 33-67 years (mean: 54 years) were treated with 31 sessions of intra-arterial antiblastic infusion, 5 of them for neoadjuvant purposes (Group 1), 5 for palliation in unresectable tumors (Group 2) and 8 for cutaneous recurrences after mastectomy (Group 3). Results. 2/5 CR and 3/5 PR were obtained in Group 1; 2/5 lesions were made resectable and 3/5 RP obtained in stage III or unresectable lesions (Group 2). Finally, 3/8 CR, 3/8 PR, 1/8 SD and 1/8 PD were observed in Group 3. An objective response according to WHO criteria was demonstrated in 15/18 cases (88%). We had no post-treatment hematologic complications, but one patient presented focal subcutaneous sclerosis and one cutaneous necrosis. Conclusions. The morphological efficacy of intraarterial antiblastic infusion in our series was similar to that of other series. No definitive conclusions can be drawn yet about clinical results and long-term survival. This poorly invasive and low risk procedure, which should be combined with other treatments, permits to reduce the extent of surgery and to treat skin recurrences.
| Original language | Italian |
|---|---|
| Pages (from-to) | 211-216 |
| Number of pages | 6 |
| Journal | Radiologia Medica |
| Volume | 95 |
| Issue number | 3 |
| Publication status | Published - Mar 1998 |
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ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
Terapia antiblastica per via intrarteriosa del carcinoma della mammella. / Roversi, Rigoantonio; Rossi, Giuseppe; Ricci, Stefano; Roversi, Marina; Pinelli, Gianluigi; Cavallo, Giovanna.
In: Radiologia Medica, Vol. 95, No. 3, 03.1998, p. 211-216.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Terapia antiblastica per via intrarteriosa del carcinoma della mammella
AU - Roversi, Rigoantonio
AU - Rossi, Giuseppe
AU - Ricci, Stefano
AU - Roversi, Marina
AU - Pinelli, Gianluigi
AU - Cavallo, Giovanna
PY - 1998/3
Y1 - 1998/3
N2 - Purpose. To report our personal experience with the locoregional treatment of breast cancer. Material and methods. Eighteen patients aged 33-67 years (mean: 54 years) were treated with 31 sessions of intra-arterial antiblastic infusion, 5 of them for neoadjuvant purposes (Group 1), 5 for palliation in unresectable tumors (Group 2) and 8 for cutaneous recurrences after mastectomy (Group 3). Results. 2/5 CR and 3/5 PR were obtained in Group 1; 2/5 lesions were made resectable and 3/5 RP obtained in stage III or unresectable lesions (Group 2). Finally, 3/8 CR, 3/8 PR, 1/8 SD and 1/8 PD were observed in Group 3. An objective response according to WHO criteria was demonstrated in 15/18 cases (88%). We had no post-treatment hematologic complications, but one patient presented focal subcutaneous sclerosis and one cutaneous necrosis. Conclusions. The morphological efficacy of intraarterial antiblastic infusion in our series was similar to that of other series. No definitive conclusions can be drawn yet about clinical results and long-term survival. This poorly invasive and low risk procedure, which should be combined with other treatments, permits to reduce the extent of surgery and to treat skin recurrences.
AB - Purpose. To report our personal experience with the locoregional treatment of breast cancer. Material and methods. Eighteen patients aged 33-67 years (mean: 54 years) were treated with 31 sessions of intra-arterial antiblastic infusion, 5 of them for neoadjuvant purposes (Group 1), 5 for palliation in unresectable tumors (Group 2) and 8 for cutaneous recurrences after mastectomy (Group 3). Results. 2/5 CR and 3/5 PR were obtained in Group 1; 2/5 lesions were made resectable and 3/5 RP obtained in stage III or unresectable lesions (Group 2). Finally, 3/8 CR, 3/8 PR, 1/8 SD and 1/8 PD were observed in Group 3. An objective response according to WHO criteria was demonstrated in 15/18 cases (88%). We had no post-treatment hematologic complications, but one patient presented focal subcutaneous sclerosis and one cutaneous necrosis. Conclusions. The morphological efficacy of intraarterial antiblastic infusion in our series was similar to that of other series. No definitive conclusions can be drawn yet about clinical results and long-term survival. This poorly invasive and low risk procedure, which should be combined with other treatments, permits to reduce the extent of surgery and to treat skin recurrences.
KW - Breast cancer, intra-arterial infusion
KW - Breast, cancer
UR - http://www.scopus.com/inward/record.url?scp=2542480097&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=2542480097&partnerID=8YFLogxK
M3 - Articolo
C2 - 9638168
AN - SCOPUS:2542480097
VL - 95
SP - 211
EP - 216
JO - Radiologia Medica
JF - Radiologia Medica
SN - 0033-8362
IS - 3
ER -