Trombolisi intra-arteriosa associata ad ultrasuoni nell'embolia polmonare submassiva

primo caso italiano

Translated title of the contribution: Intra-arterial thrombolysis facilitated by ultrasound in submassive pulmonary embolism: First Italian case

Anna Salerno, Azeem Latib, Carlo Ballarotto, Stefano Cappio, Paolo G. Camici, Antonio Colombo

Research output: Contribution to journalArticle

Abstract

A 76-year-old woman presented with a one-week history of dyspnea on minimal exertion and at rest. In the emergency room she underwent echocardiography and thoracic computed tomography scan with diagnosis of bilateral pulmonary embolism. Due to right ventricular dilatation and increasing values of NT-probrain natriuretic peptide, both markers of high risk that classify pulmonary embolism as "submassive" according to current international guidelines, we opted for thrombolysis. The patient underwent intra-arterial bilateral pulmonary thrombolysis facilitated by ultrasound, the first case in Italy. The patient recovered from pulmonary embolism after 10h of therapy, with improved gas exchange and symptoms. Subsequently, she developed arterial bleeding at the puncture site, due to accidental puncture of a branch of the femoral artery. The patient was treated with percutaneous embolization and transfusions. In patients with pulmonary embolism, even if not massive, thrombolysis should be considered, especially in the presence of high-risk markers. Direct intra-arterial pulmonary thrombolysis, facilitated by ultrasound, is an effective procedure that provides an alternative to conventional thrombolysis with the advantage of a lower thrombolytic dose.

Original languageItalian
Pages (from-to)289-292
Number of pages4
JournalGiornale Italiano di Cardiologia
Volume14
Issue number4
Publication statusPublished - Apr 2013

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Pulmonary Embolism
Punctures
Lung
Natriuretic Peptides
Femoral Artery
Dyspnea
Italy
Echocardiography
Hospital Emergency Service
Dilatation
Thorax
Gases
Tomography
Guidelines
Hemorrhage
Therapeutics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Trombolisi intra-arteriosa associata ad ultrasuoni nell'embolia polmonare submassiva : primo caso italiano. / Salerno, Anna; Latib, Azeem; Ballarotto, Carlo; Cappio, Stefano; Camici, Paolo G.; Colombo, Antonio.

In: Giornale Italiano di Cardiologia, Vol. 14, No. 4, 04.2013, p. 289-292.

Research output: Contribution to journalArticle

Salerno, A, Latib, A, Ballarotto, C, Cappio, S, Camici, PG & Colombo, A 2013, 'Trombolisi intra-arteriosa associata ad ultrasuoni nell'embolia polmonare submassiva: primo caso italiano', Giornale Italiano di Cardiologia, vol. 14, no. 4, pp. 289-292.
Salerno, Anna ; Latib, Azeem ; Ballarotto, Carlo ; Cappio, Stefano ; Camici, Paolo G. ; Colombo, Antonio. / Trombolisi intra-arteriosa associata ad ultrasuoni nell'embolia polmonare submassiva : primo caso italiano. In: Giornale Italiano di Cardiologia. 2013 ; Vol. 14, No. 4. pp. 289-292.
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