Intra-Operative Contrast Cholangiography in Living Donor Liver Transplantation: The ISMETT Experience

D. Pagano, D. Cintorino, S. Li Petri, M. Paci, A. Tropea, C. Ricotta, P. Bonsignore, M. C. Saffioti, M. Spada, R. Miraglia, B. G. Gridelli, S. Gruttadauria

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2 Citations (Scopus)

Abstract

Background We evaluated the clinical impact of donor biliary anatomy discrepancies (DBAD) achieved by comparing pre-operative evaluation obtained with magnetic resonance (MR)/magnetic resonance cholangiopancreatography (MRCP) imaging, with intra-operative cholangiography (IOC) on the living related liver donor (LDLT) and recipient. Methods This single-center, retrospective study included 97 consecutive adult-to-adult (A2A) LDLT performed in our hospital in the last 12 years. Donor sex and age, living donors with biliary and/or vascular anomalies, recipient age, sex, primary etiology, re-transplantation, Model of End-Stage Liver Disease score, co-morbidities, arterial and biliary recipient complications assessed on the basis of clinical follow-up were collected and analyzed for significance through the use of a multivariate linear regression model. Results Biliary complications in the donor (DBC) were detected in 8 (8.2%) cases. Biliary complications in the recipients (RBC) were detected in 38 (39%) cases. DBADs were found in 32 (33%) cases and resulted strictly related to RBC (P =.05). Conclusions After adjusting for co-variables, results of the linear regression analysis confirmed that DBAD is an independent predictor of RBC, but it is not significantly associated with vascular complications or patient survival. We showed that RBCs after LDLT were influenced by DBAD.

Original languageEnglish
Pages (from-to)2159-2160
Number of pages2
JournalTransplantation Proceedings
Volume47
Issue number7
DOIs
Publication statusPublished - Sep 1 2015

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Cholangiography
Living Donors
Liver Transplantation
Tissue Donors
Linear Models
Anatomy
Blood Vessels
Magnetic Resonance Cholangiopancreatography
End Stage Liver Disease
Magnetic Resonance Spectroscopy
Retrospective Studies
Transplantation
Regression Analysis
Magnetic Resonance Imaging
Morbidity
Survival
Liver

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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Intra-Operative Contrast Cholangiography in Living Donor Liver Transplantation : The ISMETT Experience. / Pagano, D.; Cintorino, D.; Li Petri, S.; Paci, M.; Tropea, A.; Ricotta, C.; Bonsignore, P.; Saffioti, M. C.; Spada, M.; Miraglia, R.; Gridelli, B. G.; Gruttadauria, S.

In: Transplantation Proceedings, Vol. 47, No. 7, 01.09.2015, p. 2159-2160.

Research output: Contribution to journalArticle

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abstract = "Background We evaluated the clinical impact of donor biliary anatomy discrepancies (DBAD) achieved by comparing pre-operative evaluation obtained with magnetic resonance (MR)/magnetic resonance cholangiopancreatography (MRCP) imaging, with intra-operative cholangiography (IOC) on the living related liver donor (LDLT) and recipient. Methods This single-center, retrospective study included 97 consecutive adult-to-adult (A2A) LDLT performed in our hospital in the last 12 years. Donor sex and age, living donors with biliary and/or vascular anomalies, recipient age, sex, primary etiology, re-transplantation, Model of End-Stage Liver Disease score, co-morbidities, arterial and biliary recipient complications assessed on the basis of clinical follow-up were collected and analyzed for significance through the use of a multivariate linear regression model. Results Biliary complications in the donor (DBC) were detected in 8 (8.2{\%}) cases. Biliary complications in the recipients (RBC) were detected in 38 (39{\%}) cases. DBADs were found in 32 (33{\%}) cases and resulted strictly related to RBC (P =.05). Conclusions After adjusting for co-variables, results of the linear regression analysis confirmed that DBAD is an independent predictor of RBC, but it is not significantly associated with vascular complications or patient survival. We showed that RBCs after LDLT were influenced by DBAD.",
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AU - Pagano, D.

AU - Cintorino, D.

AU - Li Petri, S.

AU - Paci, M.

AU - Tropea, A.

AU - Ricotta, C.

AU - Bonsignore, P.

AU - Saffioti, M. C.

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AU - Gridelli, B. G.

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