Intra-Operative Contrast Cholangiography in Living Donor Liver Transplantation: The ISMETT Experience

D. Pagano, D. Cintorino, S. Li Petri, M. Paci, A. Tropea, C. Ricotta, P. Bonsignore, M. C. Saffioti, M. Spada, R. Miraglia, B. G. Gridelli, S. Gruttadauria

Research output: Contribution to journalArticlepeer-review


Background We evaluated the clinical impact of donor biliary anatomy discrepancies (DBAD) achieved by comparing pre-operative evaluation obtained with magnetic resonance (MR)/magnetic resonance cholangiopancreatography (MRCP) imaging, with intra-operative cholangiography (IOC) on the living related liver donor (LDLT) and recipient. Methods This single-center, retrospective study included 97 consecutive adult-to-adult (A2A) LDLT performed in our hospital in the last 12 years. Donor sex and age, living donors with biliary and/or vascular anomalies, recipient age, sex, primary etiology, re-transplantation, Model of End-Stage Liver Disease score, co-morbidities, arterial and biliary recipient complications assessed on the basis of clinical follow-up were collected and analyzed for significance through the use of a multivariate linear regression model. Results Biliary complications in the donor (DBC) were detected in 8 (8.2%) cases. Biliary complications in the recipients (RBC) were detected in 38 (39%) cases. DBADs were found in 32 (33%) cases and resulted strictly related to RBC (P =.05). Conclusions After adjusting for co-variables, results of the linear regression analysis confirmed that DBAD is an independent predictor of RBC, but it is not significantly associated with vascular complications or patient survival. We showed that RBCs after LDLT were influenced by DBAD.

Original languageEnglish
Pages (from-to)2159-2160
Number of pages2
JournalTransplantation Proceedings
Issue number7
Publication statusPublished - Sep 1 2015

ASJC Scopus subject areas

  • Surgery
  • Transplantation


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