Intracavitary cisplatin (CDDP) in the treatment of metastatic pericardial involvement from breast and lung cancer

M. Tondini, G. Rocco, C. Bianchi, C. Severi, D. Corbellini

Research output: Contribution to journalArticlepeer-review

Abstract

Seven patients with lung cancer and two with breast cancer developed a symptomatic pericardial effusion and were treated with intrapericardial cisplatin (CDDP), In all of the patients, cytological confirmation of metastatic effusion was achieved. A single cycle with 10 mg of cisplatin diluted in 20 ml of normal saline was administered for five consecutive days via an intrapericardial catheter. Control of recurrent effusions was obtained in eight of the nine patients, No significant side-effects were observed.

Original languageEnglish
Pages (from-to)86-88
Number of pages3
JournalMonaldi Archives for Chest Disease - Cardiac Series
Volume50
Issue number2
Publication statusPublished - 1995

Keywords

  • Intrapericardial chemotherapy
  • Pericardial metastasis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine

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