Intracerebroventricular injection of capsaicin or substance P provokes the micturition reflex in the rat

B. Dib, M. M. Corsi, A. Fulgenzi, M. E. Ferrero, M. Falchi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Acute intracerebroventricular injection of 25 μg capsaicin or 40 μg substance P in isotonic saline elicited approximately similar effects on the micturition reflex, but capsaicin had twice as much effect as substance P. This effect is specific, since acute intracerebroventricular injection of isotonic saline did not produce the micturition reflex. It can be hypothesized that capsaicin and substance P may act on the brain micturition centers directly or by mediation of neuropeptides such as tachykinins, but other hypotheses are also made.

Original languageEnglish
Pages (from-to)109-114
Number of pages6
JournalInternational Journal of Tissue Reactions
Volume20
Issue number4
Publication statusPublished - 1998

Fingerprint

Urination
Capsaicin
Substance P
Reflex
Injections
Tachykinins
Neuropeptides
Brain

ASJC Scopus subject areas

  • Cell Biology
  • Physiology

Cite this

Intracerebroventricular injection of capsaicin or substance P provokes the micturition reflex in the rat. / Dib, B.; Corsi, M. M.; Fulgenzi, A.; Ferrero, M. E.; Falchi, M.

In: International Journal of Tissue Reactions, Vol. 20, No. 4, 1998, p. 109-114.

Research output: Contribution to journalArticle

@article{24203bd537a04068ae09f30ac07d42b4,
title = "Intracerebroventricular injection of capsaicin or substance P provokes the micturition reflex in the rat",
abstract = "Acute intracerebroventricular injection of 25 μg capsaicin or 40 μg substance P in isotonic saline elicited approximately similar effects on the micturition reflex, but capsaicin had twice as much effect as substance P. This effect is specific, since acute intracerebroventricular injection of isotonic saline did not produce the micturition reflex. It can be hypothesized that capsaicin and substance P may act on the brain micturition centers directly or by mediation of neuropeptides such as tachykinins, but other hypotheses are also made.",
author = "B. Dib and Corsi, {M. M.} and A. Fulgenzi and Ferrero, {M. E.} and M. Falchi",
year = "1998",
language = "English",
volume = "20",
pages = "109--114",
journal = "International Journal of Tissue Reactions",
issn = "0250-0868",
publisher = "Bioscience Ediprint Inc.",
number = "4",

}

TY - JOUR

T1 - Intracerebroventricular injection of capsaicin or substance P provokes the micturition reflex in the rat

AU - Dib, B.

AU - Corsi, M. M.

AU - Fulgenzi, A.

AU - Ferrero, M. E.

AU - Falchi, M.

PY - 1998

Y1 - 1998

N2 - Acute intracerebroventricular injection of 25 μg capsaicin or 40 μg substance P in isotonic saline elicited approximately similar effects on the micturition reflex, but capsaicin had twice as much effect as substance P. This effect is specific, since acute intracerebroventricular injection of isotonic saline did not produce the micturition reflex. It can be hypothesized that capsaicin and substance P may act on the brain micturition centers directly or by mediation of neuropeptides such as tachykinins, but other hypotheses are also made.

AB - Acute intracerebroventricular injection of 25 μg capsaicin or 40 μg substance P in isotonic saline elicited approximately similar effects on the micturition reflex, but capsaicin had twice as much effect as substance P. This effect is specific, since acute intracerebroventricular injection of isotonic saline did not produce the micturition reflex. It can be hypothesized that capsaicin and substance P may act on the brain micturition centers directly or by mediation of neuropeptides such as tachykinins, but other hypotheses are also made.

UR - http://www.scopus.com/inward/record.url?scp=0032462354&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032462354&partnerID=8YFLogxK

M3 - Article

C2 - 10093793

AN - SCOPUS:0032462354

VL - 20

SP - 109

EP - 114

JO - International Journal of Tissue Reactions

JF - International Journal of Tissue Reactions

SN - 0250-0868

IS - 4

ER -