Abstract
Acute intracerebroventricular injection of 25 μg capsaicin or 40 μg substance P in isotonic saline elicited approximately similar effects on the micturition reflex, but capsaicin had twice as much effect as substance P. This effect is specific, since acute intracerebroventricular injection of isotonic saline did not produce the micturition reflex. It can be hypothesized that capsaicin and substance P may act on the brain micturition centers directly or by mediation of neuropeptides such as tachykinins, but other hypotheses are also made.
| Original language | English |
|---|---|
| Pages (from-to) | 109-114 |
| Number of pages | 6 |
| Journal | International Journal of Tissue Reactions |
| Volume | 20 |
| Issue number | 4 |
| Publication status | Published - 1998 |
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ASJC Scopus subject areas
- Cell Biology
- Physiology
Cite this
Intracerebroventricular injection of capsaicin or substance P provokes the micturition reflex in the rat. / Dib, B.; Corsi, M. M.; Fulgenzi, A.; Ferrero, M. E.; Falchi, M.
In: International Journal of Tissue Reactions, Vol. 20, No. 4, 1998, p. 109-114.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Intracerebroventricular injection of capsaicin or substance P provokes the micturition reflex in the rat
AU - Dib, B.
AU - Corsi, M. M.
AU - Fulgenzi, A.
AU - Ferrero, M. E.
AU - Falchi, M.
PY - 1998
Y1 - 1998
N2 - Acute intracerebroventricular injection of 25 μg capsaicin or 40 μg substance P in isotonic saline elicited approximately similar effects on the micturition reflex, but capsaicin had twice as much effect as substance P. This effect is specific, since acute intracerebroventricular injection of isotonic saline did not produce the micturition reflex. It can be hypothesized that capsaicin and substance P may act on the brain micturition centers directly or by mediation of neuropeptides such as tachykinins, but other hypotheses are also made.
AB - Acute intracerebroventricular injection of 25 μg capsaicin or 40 μg substance P in isotonic saline elicited approximately similar effects on the micturition reflex, but capsaicin had twice as much effect as substance P. This effect is specific, since acute intracerebroventricular injection of isotonic saline did not produce the micturition reflex. It can be hypothesized that capsaicin and substance P may act on the brain micturition centers directly or by mediation of neuropeptides such as tachykinins, but other hypotheses are also made.
UR - http://www.scopus.com/inward/record.url?scp=0032462354&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032462354&partnerID=8YFLogxK
M3 - Article
C2 - 10093793
AN - SCOPUS:0032462354
VL - 20
SP - 109
EP - 114
JO - International Journal of Tissue Reactions
JF - International Journal of Tissue Reactions
SN - 0250-0868
IS - 4
ER -