Intracoronary ST-segment shift soon after elective percutaneous coronary intervention accurately predicts periprocedural myocardial injury

Vruyr Balian, Michele Galli, Claudio Marcassa, Gianni Cecchin, Maurice Child, Fabio Barlocco, Ettore Petrucci, Giulia Filippini, Riccardo Michi, Marco Onofri

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND - Elevation of cardiac biomarkers after coronary angioplasty (percutaneous coronary intervention [PCI]) reflects periprocedural myocardial damage and is associated with adverse cardiac events. We assessed whether periprocedural myocardial damage that occurs despite successful PCI could be rapidly and easily identified by intracoronary ST-segment recording with the use of a catheter guidewire. METHODS AND RESULTS - In 108 consecutive stable patients undergoing elective single-vessel PCI, we recorded unipolar ECG from the intracoronary guidewire in the distal coronary before PCI and 2 minutes after the last balloon inflation. After PCI, intracoronary ST-segment shift ≥1 mm from baseline was considered significant. Troponin I levels were measured at baseline and at 8 and 24 hours after intervention, and myocardial damage was defined as troponin I increase above the upper normal value after intervention. All patients had normal cardiac marker values before PCI, and PCI was successful in all (residual stenosis

Original languageEnglish
Pages (from-to)1948-1954
Number of pages7
JournalCirculation
Volume114
Issue number18
DOIs
Publication statusPublished - Oct 2006

Keywords

  • Angioplasty
  • Electrocardiography
  • Infarction
  • Revascularization

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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