Intracorporeal versus extracorporeal anastomosis. Results from a multicentre comparative study on 512 right-sided colorectal cancers

Marco Milone, Ugo Elmore, Enrico Di Salvo, Paolo Delrio, Luigi Bucci, Giuseppe Paolo Ferulano, Carmine Napolitano, Maria Rachele Angiolini, Umberto Bracale, Marco Clemente, Michele D’ambra, Gaetano Luglio, Mario Musella, Ugo Pace, Riccardo Rosati, Francesco Milone

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Background: Although nowadays considered as feasible and effective surgery in terms of short- and long-term results and oncological radicality, laparoscopic right colectomy is performed by a small number of surgeons, and in the vast majority of cases, this technique was performed with an extracorporeal anastomosis. Current literature failed to solve the controversies between intracorporeal and extracorporeal anastomosis after laparoscopic right colectomy. Methods: A multicenter case-controlled study has been designed, including 286 patients who underwent laparoscopic right hemicolectomy with intracorporeal anastomosis (IA) compared with 226 matched patients who underwent laparoscopic right hemicolectomy with extracorporeal anastomosis (EA). Results: There was no significant difference in terms of age, sex, BMI, and ASA score between the two groups. Surgical post history, tumor localization, and stage of disease according to AJCC/UICC TNM were similar too. Although similar oncologic radicality in term of number of lymph nodes harvested (25.7 ± 10.7 of IA group vs. 24.8 ± 8.7 of EA group; p = 0.3), as well as similar operative time (166 ± 43.7 min. in IA group vs. 157.5 ± 67.2 min in EA group) have been registered, time to flatus was statistically lower after intracorporeal anastomosis (40.8 ± 24.3 h in TLRC group vs. 55.2 ± 19.2 h in LARC group; p 

Original languageEnglish
Pages (from-to)2314-2320
Number of pages7
JournalSurgical Endoscopy and Other Interventional Techniques
Volume29
Issue number8
DOIs
Publication statusPublished - Aug 25 2015

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Colectomy
Multicenter Studies
Colorectal Neoplasms
Flatulence
Operative Time
Lymph Nodes
History
Neoplasms
Surgeons

Keywords

  • Anastomosis
  • Extracorporeal
  • Intracorporeal
  • Right colectomy
  • Totally laparoscopic
  • Video-assisted

ASJC Scopus subject areas

  • Surgery
  • Medicine(all)

Cite this

Intracorporeal versus extracorporeal anastomosis. Results from a multicentre comparative study on 512 right-sided colorectal cancers. / Milone, Marco; Elmore, Ugo; Di Salvo, Enrico; Delrio, Paolo; Bucci, Luigi; Ferulano, Giuseppe Paolo; Napolitano, Carmine; Angiolini, Maria Rachele; Bracale, Umberto; Clemente, Marco; D’ambra, Michele; Luglio, Gaetano; Musella, Mario; Pace, Ugo; Rosati, Riccardo; Milone, Francesco.

In: Surgical Endoscopy and Other Interventional Techniques, Vol. 29, No. 8, 25.08.2015, p. 2314-2320.

Research output: Contribution to journalArticle

Milone, M, Elmore, U, Di Salvo, E, Delrio, P, Bucci, L, Ferulano, GP, Napolitano, C, Angiolini, MR, Bracale, U, Clemente, M, D’ambra, M, Luglio, G, Musella, M, Pace, U, Rosati, R & Milone, F 2015, 'Intracorporeal versus extracorporeal anastomosis. Results from a multicentre comparative study on 512 right-sided colorectal cancers', Surgical Endoscopy and Other Interventional Techniques, vol. 29, no. 8, pp. 2314-2320. https://doi.org/10.1007/s00464-014-3950-7
Milone, Marco ; Elmore, Ugo ; Di Salvo, Enrico ; Delrio, Paolo ; Bucci, Luigi ; Ferulano, Giuseppe Paolo ; Napolitano, Carmine ; Angiolini, Maria Rachele ; Bracale, Umberto ; Clemente, Marco ; D’ambra, Michele ; Luglio, Gaetano ; Musella, Mario ; Pace, Ugo ; Rosati, Riccardo ; Milone, Francesco. / Intracorporeal versus extracorporeal anastomosis. Results from a multicentre comparative study on 512 right-sided colorectal cancers. In: Surgical Endoscopy and Other Interventional Techniques. 2015 ; Vol. 29, No. 8. pp. 2314-2320.
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AU - Milone, Marco

AU - Elmore, Ugo

AU - Di Salvo, Enrico

AU - Delrio, Paolo

AU - Bucci, Luigi

AU - Ferulano, Giuseppe Paolo

AU - Napolitano, Carmine

AU - Angiolini, Maria Rachele

AU - Bracale, Umberto

AU - Clemente, Marco

AU - D’ambra, Michele

AU - Luglio, Gaetano

AU - Musella, Mario

AU - Pace, Ugo

AU - Rosati, Riccardo

AU - Milone, Francesco

PY - 2015/8/25

Y1 - 2015/8/25

N2 - Background: Although nowadays considered as feasible and effective surgery in terms of short- and long-term results and oncological radicality, laparoscopic right colectomy is performed by a small number of surgeons, and in the vast majority of cases, this technique was performed with an extracorporeal anastomosis. Current literature failed to solve the controversies between intracorporeal and extracorporeal anastomosis after laparoscopic right colectomy. Methods: A multicenter case-controlled study has been designed, including 286 patients who underwent laparoscopic right hemicolectomy with intracorporeal anastomosis (IA) compared with 226 matched patients who underwent laparoscopic right hemicolectomy with extracorporeal anastomosis (EA). Results: There was no significant difference in terms of age, sex, BMI, and ASA score between the two groups. Surgical post history, tumor localization, and stage of disease according to AJCC/UICC TNM were similar too. Although similar oncologic radicality in term of number of lymph nodes harvested (25.7 ± 10.7 of IA group vs. 24.8 ± 8.7 of EA group; p = 0.3), as well as similar operative time (166 ± 43.7 min. in IA group vs. 157.5 ± 67.2 min in EA group) have been registered, time to flatus was statistically lower after intracorporeal anastomosis (40.8 ± 24.3 h in TLRC group vs. 55.2 ± 19.2 h in LARC group; p 

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