Abstract
Phakomatosis refers to several malformation syndromes with simultaneous involvement of the skin, the eye, and the central nervous system by developmental lesions. Speckled lentiginous nevus (SLN), a subtype of congenital melanocytic nevi, is usually an isolate, harmless finding. Here, we report the case of a 52-year-old woman with congenital left laterocervical SLN associated with an ipsilateral intracranial extra-axial cavernous angioma, a yet not described association to date. After revision of the literature, we suggest that both these lesions could be correlated in the setting of an atypical, yet unclassifiable form of phakomatosis, such as phakomatosis pigmentovascularis or SLN syndrome. We also propose that patients with bizarre, geometrical, pigmented or vascular cervicocranial skin lesions should undergo a thorough neurologic and ophthalmologic evaluation.
| Original language | English |
|---|---|
| Pages (from-to) | 841-844 |
| Number of pages | 4 |
| Journal | Neurological Sciences |
| Volume | 31 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Dec 2010 |
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Keywords
- Intracranial cavernous angioma
- Phakomatosis
- Speckled lentiginous nevus
ASJC Scopus subject areas
- Clinical Neurology
- Psychiatry and Mental health
- Dermatology
Cite this
Intracranial cavernoma and speckled lentiginous nevus : Extending the spectrum of phakomatoses? / Boncoraglio, Giorgio B.; Parati, Eugenio A.; Ciceri, Elisa; Rinaldi, Rosa; Capella, Giovanni L.
In: Neurological Sciences, Vol. 31, No. 6, 12.2010, p. 841-844.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Intracranial cavernoma and speckled lentiginous nevus
T2 - Extending the spectrum of phakomatoses?
AU - Boncoraglio, Giorgio B.
AU - Parati, Eugenio A.
AU - Ciceri, Elisa
AU - Rinaldi, Rosa
AU - Capella, Giovanni L.
PY - 2010/12
Y1 - 2010/12
N2 - Phakomatosis refers to several malformation syndromes with simultaneous involvement of the skin, the eye, and the central nervous system by developmental lesions. Speckled lentiginous nevus (SLN), a subtype of congenital melanocytic nevi, is usually an isolate, harmless finding. Here, we report the case of a 52-year-old woman with congenital left laterocervical SLN associated with an ipsilateral intracranial extra-axial cavernous angioma, a yet not described association to date. After revision of the literature, we suggest that both these lesions could be correlated in the setting of an atypical, yet unclassifiable form of phakomatosis, such as phakomatosis pigmentovascularis or SLN syndrome. We also propose that patients with bizarre, geometrical, pigmented or vascular cervicocranial skin lesions should undergo a thorough neurologic and ophthalmologic evaluation.
AB - Phakomatosis refers to several malformation syndromes with simultaneous involvement of the skin, the eye, and the central nervous system by developmental lesions. Speckled lentiginous nevus (SLN), a subtype of congenital melanocytic nevi, is usually an isolate, harmless finding. Here, we report the case of a 52-year-old woman with congenital left laterocervical SLN associated with an ipsilateral intracranial extra-axial cavernous angioma, a yet not described association to date. After revision of the literature, we suggest that both these lesions could be correlated in the setting of an atypical, yet unclassifiable form of phakomatosis, such as phakomatosis pigmentovascularis or SLN syndrome. We also propose that patients with bizarre, geometrical, pigmented or vascular cervicocranial skin lesions should undergo a thorough neurologic and ophthalmologic evaluation.
KW - Intracranial cavernous angioma
KW - Phakomatosis
KW - Speckled lentiginous nevus
UR - http://www.scopus.com/inward/record.url?scp=78650517411&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78650517411&partnerID=8YFLogxK
U2 - 10.1007/s10072-010-0401-7
DO - 10.1007/s10072-010-0401-7
M3 - Article
VL - 31
SP - 841
EP - 844
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - 6
ER -