Intracranial extension of orbital inflammatory pseudotumor

A case report and literature review

Enrico Tedeschi, Lorenzo Ugga, Ferdinando Caranci, Francesca Califano, Sirio Cocozza, Giacomo Lus, Arturo Brunetti

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Orbital inflammatory pseudotumor is a rare inflammatory condition of unknown cause that may extend intracranially, usually as a dural-based infiltrate. Here we report the first case of orbital pseudotumor presenting with intra-axial Magnetic Resonance Imaging (MRI) changes. Case presentation: A 57-year-old white female, with a 3-month history of headache and right palpebral edema, presented with marked right temporal lobe edema with ominous MRI appearance, and ipsilateral alterations of orbital and periorbital structures. Following steroid therapy, both intracranial and orbital involvement dramatically improved. Conclusion: Orbital inflammatory pseudotumor with chronic inflammation may infrequently present with intracranial involvement, mimicking more aggressive diseases, even showing intra-axial enhancement after i.v. contrast administration in brain MRI. Awareness of this possibility may help neurologists to choose the appropriate therapeutic approach.

Original languageEnglish
Article number29
JournalBMC Neurology
Volume16
Issue number1
DOIs
Publication statusPublished - Feb 29 2016

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Orbital Pseudotumor
Magnetic Resonance Imaging
Edema
Eyelids
Temporal Lobe
Headache
Steroids
Inflammation
Brain
Therapeutics

Keywords

  • Intracranial extension
  • Magnetic resonance imaging
  • MRI
  • Orbital inflammatory pseudotumor
  • Orbital mass

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Tedeschi, E., Ugga, L., Caranci, F., Califano, F., Cocozza, S., Lus, G., & Brunetti, A. (2016). Intracranial extension of orbital inflammatory pseudotumor: A case report and literature review. BMC Neurology, 16(1), [29]. https://doi.org/10.1186/s12883-016-0550-2

Intracranial extension of orbital inflammatory pseudotumor : A case report and literature review. / Tedeschi, Enrico; Ugga, Lorenzo; Caranci, Ferdinando; Califano, Francesca; Cocozza, Sirio; Lus, Giacomo; Brunetti, Arturo.

In: BMC Neurology, Vol. 16, No. 1, 29, 29.02.2016.

Research output: Contribution to journalArticle

Tedeschi, E, Ugga, L, Caranci, F, Califano, F, Cocozza, S, Lus, G & Brunetti, A 2016, 'Intracranial extension of orbital inflammatory pseudotumor: A case report and literature review', BMC Neurology, vol. 16, no. 1, 29. https://doi.org/10.1186/s12883-016-0550-2
Tedeschi, Enrico ; Ugga, Lorenzo ; Caranci, Ferdinando ; Califano, Francesca ; Cocozza, Sirio ; Lus, Giacomo ; Brunetti, Arturo. / Intracranial extension of orbital inflammatory pseudotumor : A case report and literature review. In: BMC Neurology. 2016 ; Vol. 16, No. 1.
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