TY - JOUR
T1 - Intracranial extension of orbital inflammatory pseudotumor
T2 - A case report and literature review
AU - Tedeschi, Enrico
AU - Ugga, Lorenzo
AU - Caranci, Ferdinando
AU - Califano, Francesca
AU - Cocozza, Sirio
AU - Lus, Giacomo
AU - Brunetti, Arturo
PY - 2016/2/29
Y1 - 2016/2/29
N2 - Background: Orbital inflammatory pseudotumor is a rare inflammatory condition of unknown cause that may extend intracranially, usually as a dural-based infiltrate. Here we report the first case of orbital pseudotumor presenting with intra-axial Magnetic Resonance Imaging (MRI) changes. Case presentation: A 57-year-old white female, with a 3-month history of headache and right palpebral edema, presented with marked right temporal lobe edema with ominous MRI appearance, and ipsilateral alterations of orbital and periorbital structures. Following steroid therapy, both intracranial and orbital involvement dramatically improved. Conclusion: Orbital inflammatory pseudotumor with chronic inflammation may infrequently present with intracranial involvement, mimicking more aggressive diseases, even showing intra-axial enhancement after i.v. contrast administration in brain MRI. Awareness of this possibility may help neurologists to choose the appropriate therapeutic approach.
AB - Background: Orbital inflammatory pseudotumor is a rare inflammatory condition of unknown cause that may extend intracranially, usually as a dural-based infiltrate. Here we report the first case of orbital pseudotumor presenting with intra-axial Magnetic Resonance Imaging (MRI) changes. Case presentation: A 57-year-old white female, with a 3-month history of headache and right palpebral edema, presented with marked right temporal lobe edema with ominous MRI appearance, and ipsilateral alterations of orbital and periorbital structures. Following steroid therapy, both intracranial and orbital involvement dramatically improved. Conclusion: Orbital inflammatory pseudotumor with chronic inflammation may infrequently present with intracranial involvement, mimicking more aggressive diseases, even showing intra-axial enhancement after i.v. contrast administration in brain MRI. Awareness of this possibility may help neurologists to choose the appropriate therapeutic approach.
KW - Intracranial extension
KW - Magnetic resonance imaging
KW - MRI
KW - Orbital inflammatory pseudotumor
KW - Orbital mass
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U2 - 10.1186/s12883-016-0550-2
DO - 10.1186/s12883-016-0550-2
M3 - Article
AN - SCOPUS:84978780946
VL - 16
JO - BMC Neurology
JF - BMC Neurology
SN - 1471-2377
IS - 1
M1 - 29
ER -