Intracranial neuromuscular choristoma: Report of a case with literature review

Antonella Coli, Mariangela Novello, Gianpiero Tamburrini, Manila Antonelli, Felice Giangaspero, Libero Lauriola

Research output: Contribution to journalArticle

Abstract

Neuromuscular choristoma (NMC), also called neuromuscular hamartoma or nerve rhabdomyoma, is a rare lesion of the spinal and cranial nerves composed of skeletal muscle intimately associated with nerve fibers. Its origin has not been precisely clarified and a malformative event, resulting from aberrant differentiation or a true neoplastic growth, have been proposed by authors. We hereby present a cerebellopontine angle NMC enlarging the eighth cranial nerve in a 3-year-old child, that histologically appeared composed of a large amount of striated muscle mixed with nerve fibers. We also provide a review of the intracranial NMC cases reported in the literature and an analysis of proposed hypotheses to explain the presence of muscle cells in nerve trunks.

Original languageEnglish
Pages (from-to)341-345
Number of pages5
JournalNeuropathology
Volume37
Issue number4
DOIs
Publication statusPublished - Aug 1 2017

Fingerprint

Choristoma
Nerve Fibers
Vestibulocochlear Nerve
Rhabdomyoma
Cerebellopontine Angle
Spinal Nerves
Hamartoma
Striated Muscle
Cranial Nerves
Muscle Cells
Skeletal Muscle
Growth

Keywords

  • choristoma
  • cranial nerves
  • neural crest
  • neuromuscular hamartoma
  • skeletal muscle

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Clinical Neurology

Cite this

Coli, A., Novello, M., Tamburrini, G., Antonelli, M., Giangaspero, F., & Lauriola, L. (2017). Intracranial neuromuscular choristoma: Report of a case with literature review. Neuropathology, 37(4), 341-345. https://doi.org/10.1111/neup.12368

Intracranial neuromuscular choristoma : Report of a case with literature review. / Coli, Antonella; Novello, Mariangela; Tamburrini, Gianpiero; Antonelli, Manila; Giangaspero, Felice; Lauriola, Libero.

In: Neuropathology, Vol. 37, No. 4, 01.08.2017, p. 341-345.

Research output: Contribution to journalArticle

Coli, A, Novello, M, Tamburrini, G, Antonelli, M, Giangaspero, F & Lauriola, L 2017, 'Intracranial neuromuscular choristoma: Report of a case with literature review', Neuropathology, vol. 37, no. 4, pp. 341-345. https://doi.org/10.1111/neup.12368
Coli, Antonella ; Novello, Mariangela ; Tamburrini, Gianpiero ; Antonelli, Manila ; Giangaspero, Felice ; Lauriola, Libero. / Intracranial neuromuscular choristoma : Report of a case with literature review. In: Neuropathology. 2017 ; Vol. 37, No. 4. pp. 341-345.
@article{3aec02b6a5234228901de45e6c3d1925,
title = "Intracranial neuromuscular choristoma: Report of a case with literature review",
abstract = "Neuromuscular choristoma (NMC), also called neuromuscular hamartoma or nerve rhabdomyoma, is a rare lesion of the spinal and cranial nerves composed of skeletal muscle intimately associated with nerve fibers. Its origin has not been precisely clarified and a malformative event, resulting from aberrant differentiation or a true neoplastic growth, have been proposed by authors. We hereby present a cerebellopontine angle NMC enlarging the eighth cranial nerve in a 3-year-old child, that histologically appeared composed of a large amount of striated muscle mixed with nerve fibers. We also provide a review of the intracranial NMC cases reported in the literature and an analysis of proposed hypotheses to explain the presence of muscle cells in nerve trunks.",
keywords = "choristoma, cranial nerves, neural crest, neuromuscular hamartoma, skeletal muscle",
author = "Antonella Coli and Mariangela Novello and Gianpiero Tamburrini and Manila Antonelli and Felice Giangaspero and Libero Lauriola",
year = "2017",
month = "8",
day = "1",
doi = "10.1111/neup.12368",
language = "English",
volume = "37",
pages = "341--345",
journal = "Neuropathology",
issn = "0919-6544",
publisher = "Wiley-Blackwell",
number = "4",

}

TY - JOUR

T1 - Intracranial neuromuscular choristoma

T2 - Report of a case with literature review

AU - Coli, Antonella

AU - Novello, Mariangela

AU - Tamburrini, Gianpiero

AU - Antonelli, Manila

AU - Giangaspero, Felice

AU - Lauriola, Libero

PY - 2017/8/1

Y1 - 2017/8/1

N2 - Neuromuscular choristoma (NMC), also called neuromuscular hamartoma or nerve rhabdomyoma, is a rare lesion of the spinal and cranial nerves composed of skeletal muscle intimately associated with nerve fibers. Its origin has not been precisely clarified and a malformative event, resulting from aberrant differentiation or a true neoplastic growth, have been proposed by authors. We hereby present a cerebellopontine angle NMC enlarging the eighth cranial nerve in a 3-year-old child, that histologically appeared composed of a large amount of striated muscle mixed with nerve fibers. We also provide a review of the intracranial NMC cases reported in the literature and an analysis of proposed hypotheses to explain the presence of muscle cells in nerve trunks.

AB - Neuromuscular choristoma (NMC), also called neuromuscular hamartoma or nerve rhabdomyoma, is a rare lesion of the spinal and cranial nerves composed of skeletal muscle intimately associated with nerve fibers. Its origin has not been precisely clarified and a malformative event, resulting from aberrant differentiation or a true neoplastic growth, have been proposed by authors. We hereby present a cerebellopontine angle NMC enlarging the eighth cranial nerve in a 3-year-old child, that histologically appeared composed of a large amount of striated muscle mixed with nerve fibers. We also provide a review of the intracranial NMC cases reported in the literature and an analysis of proposed hypotheses to explain the presence of muscle cells in nerve trunks.

KW - choristoma

KW - cranial nerves

KW - neural crest

KW - neuromuscular hamartoma

KW - skeletal muscle

UR - http://www.scopus.com/inward/record.url?scp=85013074395&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85013074395&partnerID=8YFLogxK

U2 - 10.1111/neup.12368

DO - 10.1111/neup.12368

M3 - Article

AN - SCOPUS:85013074395

VL - 37

SP - 341

EP - 345

JO - Neuropathology

JF - Neuropathology

SN - 0919-6544

IS - 4

ER -