Intracranial neuromuscular choristoma: Report of a case with literature review

Antonella Coli, Mariangela Novello, Gianpiero Tamburrini, Manila Antonelli, Felice Giangaspero, Libero Lauriola

Research output: Contribution to journalArticlepeer-review


Neuromuscular choristoma (NMC), also called neuromuscular hamartoma or nerve rhabdomyoma, is a rare lesion of the spinal and cranial nerves composed of skeletal muscle intimately associated with nerve fibers. Its origin has not been precisely clarified and a malformative event, resulting from aberrant differentiation or a true neoplastic growth, have been proposed by authors. We hereby present a cerebellopontine angle NMC enlarging the eighth cranial nerve in a 3-year-old child, that histologically appeared composed of a large amount of striated muscle mixed with nerve fibers. We also provide a review of the intracranial NMC cases reported in the literature and an analysis of proposed hypotheses to explain the presence of muscle cells in nerve trunks.

Original languageEnglish
Pages (from-to)341-345
Number of pages5
Issue number4
Publication statusPublished - Aug 1 2017


  • choristoma
  • cranial nerves
  • neural crest
  • neuromuscular hamartoma
  • skeletal muscle

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Clinical Neurology


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