Intraerythrocyte sodium in pregnancy-induced hypertension. A longitudinal study through pregnancy, puerperium and neonatal aspects

Andrea L. Tranquilli, Angela Ancona, Sabina Brandi, Laura Mazzanti, Enrico Bertoli, Ivano Testa, Rosa Anna Rabini, Carlo Romanini

Research output: Contribution to journalArticlepeer-review

Abstract

Intracellular electrolyte disorders seem to be related to pregnancy-induced hypertension as well as to essential hypertension. Intracellular Sodium storage could shift Calcium from membrane binding, thus resulting in a depolarization of excitable cells. Periarteriolar myocytes thus can be activated, resulting in the rise in peripheral vascular resistances. The intracellular electrolyte accumulation could be either due to a genetic intrinsic alteration of membranes or to the action of a circulating inhibitor. Results are reported from 75 pregnancy-induced hypertensive and 140 pregnant controls and 15 cord blood samples obtained from hypertensive and 70 from controls.

Original languageEnglish
Pages (from-to)327-336
Number of pages10
JournalHypertension in Pregnancy
VolumeB6
Issue number2
DOIs
Publication statusPublished - 1987

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Internal Medicine

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