Intralesional natural interferon alpha in the treatment of Crosti's lymphoma (primary cutaneous B follicular centre-cell lymphoma): Report of four cases

A. Parodi, C. Micalizzi, A. Rebora

Research output: Contribution to journalArticle


We describe four patients with Crosti's lymphoma, a non-Hodgkin's B-cell lymphoma of follicular centre origin, treated with intralesional natural interferon alpha (IFN). In all patients the lesions cleared. Two patients had a clinical relapse but their lesions cleared after a second course of therapy. Intralesional injections are thought to have a direct action on tumoral cells as web as a systemic effect. Given the high rate of relapse after radiotherapy (75%), natural IFN is a promising therapeutic alternative.

Original languageEnglish
Pages (from-to)105-107
Number of pages3
JournalJournal of Dermatological Treatment
Issue number2
Publication statusPublished - 1996



  • Crosti's lymphoma
  • Intralesional interferon alpha

ASJC Scopus subject areas

  • Dermatology

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