Abstract
We describe four patients with Crosti's lymphoma, a non-Hodgkin's B-cell lymphoma of follicular centre origin, treated with intralesional natural interferon alpha (IFN). In all patients the lesions cleared. Two patients had a clinical relapse but their lesions cleared after a second course of therapy. Intralesional injections are thought to have a direct action on tumoral cells as web as a systemic effect. Given the high rate of relapse after radiotherapy (75%), natural IFN is a promising therapeutic alternative.
| Original language | English |
|---|---|
| Pages (from-to) | 105-107 |
| Number of pages | 3 |
| Journal | Journal of Dermatological Treatment |
| Volume | 7 |
| Issue number | 2 |
| Publication status | Published - 1996 |
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Keywords
- Crosti's lymphoma
- Intralesional interferon alpha
ASJC Scopus subject areas
- Dermatology
Cite this
Intralesional natural interferon alpha in the treatment of Crosti's lymphoma (primary cutaneous B follicular centre-cell lymphoma) : Report of four cases. / Parodi, A.; Micalizzi, C.; Rebora, A.
In: Journal of Dermatological Treatment, Vol. 7, No. 2, 1996, p. 105-107.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Intralesional natural interferon alpha in the treatment of Crosti's lymphoma (primary cutaneous B follicular centre-cell lymphoma)
T2 - Report of four cases
AU - Parodi, A.
AU - Micalizzi, C.
AU - Rebora, A.
PY - 1996
Y1 - 1996
N2 - We describe four patients with Crosti's lymphoma, a non-Hodgkin's B-cell lymphoma of follicular centre origin, treated with intralesional natural interferon alpha (IFN). In all patients the lesions cleared. Two patients had a clinical relapse but their lesions cleared after a second course of therapy. Intralesional injections are thought to have a direct action on tumoral cells as web as a systemic effect. Given the high rate of relapse after radiotherapy (75%), natural IFN is a promising therapeutic alternative.
AB - We describe four patients with Crosti's lymphoma, a non-Hodgkin's B-cell lymphoma of follicular centre origin, treated with intralesional natural interferon alpha (IFN). In all patients the lesions cleared. Two patients had a clinical relapse but their lesions cleared after a second course of therapy. Intralesional injections are thought to have a direct action on tumoral cells as web as a systemic effect. Given the high rate of relapse after radiotherapy (75%), natural IFN is a promising therapeutic alternative.
KW - Crosti's lymphoma
KW - Intralesional interferon alpha
UR - http://www.scopus.com/inward/record.url?scp=0030018555&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030018555&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0030018555
VL - 7
SP - 105
EP - 107
JO - Journal of Dermatological Treatment
JF - Journal of Dermatological Treatment
SN - 0954-6634
IS - 2
ER -