Intralesional natural interferon alpha in the treatment of Crosti's lymphoma (primary cutaneous B follicular centre-cell lymphoma): Report of four cases

A. Parodi, C. Micalizzi, A. Rebora

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We describe four patients with Crosti's lymphoma, a non-Hodgkin's B-cell lymphoma of follicular centre origin, treated with intralesional natural interferon alpha (IFN). In all patients the lesions cleared. Two patients had a clinical relapse but their lesions cleared after a second course of therapy. Intralesional injections are thought to have a direct action on tumoral cells as web as a systemic effect. Given the high rate of relapse after radiotherapy (75%), natural IFN is a promising therapeutic alternative.

Original languageEnglish
Pages (from-to)105-107
Number of pages3
JournalJournal of Dermatological Treatment
Volume7
Issue number2
Publication statusPublished - 1996

Fingerprint

Interferon-alpha
Lymphoma
Skin
Intralesional Injections
Recurrence
B-Cell Lymphoma
Non-Hodgkin's Lymphoma
Radiotherapy
Therapeutics

Keywords

  • Crosti's lymphoma
  • Intralesional interferon alpha

ASJC Scopus subject areas

  • Dermatology

Cite this

@article{7c6a2cc3a98540e2a370cf00a48b981a,
title = "Intralesional natural interferon alpha in the treatment of Crosti's lymphoma (primary cutaneous B follicular centre-cell lymphoma): Report of four cases",
abstract = "We describe four patients with Crosti's lymphoma, a non-Hodgkin's B-cell lymphoma of follicular centre origin, treated with intralesional natural interferon alpha (IFN). In all patients the lesions cleared. Two patients had a clinical relapse but their lesions cleared after a second course of therapy. Intralesional injections are thought to have a direct action on tumoral cells as web as a systemic effect. Given the high rate of relapse after radiotherapy (75{\%}), natural IFN is a promising therapeutic alternative.",
keywords = "Crosti's lymphoma, Intralesional interferon alpha",
author = "A. Parodi and C. Micalizzi and A. Rebora",
year = "1996",
language = "English",
volume = "7",
pages = "105--107",
journal = "Journal of Dermatological Treatment",
issn = "0954-6634",
publisher = "Informa Healthcare",
number = "2",

}

TY - JOUR

T1 - Intralesional natural interferon alpha in the treatment of Crosti's lymphoma (primary cutaneous B follicular centre-cell lymphoma)

T2 - Report of four cases

AU - Parodi, A.

AU - Micalizzi, C.

AU - Rebora, A.

PY - 1996

Y1 - 1996

N2 - We describe four patients with Crosti's lymphoma, a non-Hodgkin's B-cell lymphoma of follicular centre origin, treated with intralesional natural interferon alpha (IFN). In all patients the lesions cleared. Two patients had a clinical relapse but their lesions cleared after a second course of therapy. Intralesional injections are thought to have a direct action on tumoral cells as web as a systemic effect. Given the high rate of relapse after radiotherapy (75%), natural IFN is a promising therapeutic alternative.

AB - We describe four patients with Crosti's lymphoma, a non-Hodgkin's B-cell lymphoma of follicular centre origin, treated with intralesional natural interferon alpha (IFN). In all patients the lesions cleared. Two patients had a clinical relapse but their lesions cleared after a second course of therapy. Intralesional injections are thought to have a direct action on tumoral cells as web as a systemic effect. Given the high rate of relapse after radiotherapy (75%), natural IFN is a promising therapeutic alternative.

KW - Crosti's lymphoma

KW - Intralesional interferon alpha

UR - http://www.scopus.com/inward/record.url?scp=0030018555&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030018555&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0030018555

VL - 7

SP - 105

EP - 107

JO - Journal of Dermatological Treatment

JF - Journal of Dermatological Treatment

SN - 0954-6634

IS - 2

ER -