LES DISSEMINATIONS INTRAMAMMAIRES DES CARCINOMES DU SEIN

At the conclusion of this study based on the histologic analysis of 454 mastectomy specimens carried out between 1966 and 1971 it appears that 39% of tumors which are neither central nor deep to the nipple have microscopic foci outside the main focus of the tumor of which 24% are at the level of the single nipple. The importance of these extensions is related to the size and histologic type of the adenocarcinoma: pure intraducted and infiltrating lobular forms are accompanied frequently by microscopic intramammary foci at a distance (89% and 72%) this being the opposite in cases of well differentiated and medullary forms. On the other hand no connection between the Scarff and Bloom grading is apparent except where the nipple only is involved. Finally there is a strong relation between intramammary dissemination and regional lymph node metastases.