Abstract
In the 1985-1994 period, 101 patients underwent resection for ductal pancreatic adenocarcinoma. In 27 patients, the resection was not associated with adjuvant therapies, whereas in 74 patients, it was. Intraoperative radiation therapy (IORT) was performed in 54 patients. Operative mortality and morbidity were similar in patients undergoing IORT (1.8 and 29.6%) to those undergoing resection alone (2.1 and 27.6%). Median survival of the IORT group was 17 vs 14 mo of the non-IORT group (irrespective of postoperative treatments) (ns); the local recurrence rates were 38 and 54%, respectively. The group of 74 patients undergoing adjuvant therapies had a greater survival than 27 patients with no adjuvant treatment, both at the univariate (p
| Original language | English |
|---|---|
| Pages (from-to) | 53-58 |
| Number of pages | 6 |
| Journal | International Journal of Pancreatology |
| Volume | 21 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Feb 1997 |
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Keywords
- chemotherapy
- external beam radiotherapy
- intraoperative radiation therapy
- Pancreatic cancer
- pancreatic resection
ASJC Scopus subject areas
- Oncology
- Gastroenterology
- Endocrinology
Cite this
Intraoperative and postoperative radiotherapy in pancreatic cancer. / Di Carlo, Valerio; Zerbi, Alessandro; Balzano, Gianpaolo; Villa, Eugenio.
In: International Journal of Pancreatology, Vol. 21, No. 1, 02.1997, p. 53-58.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Intraoperative and postoperative radiotherapy in pancreatic cancer
AU - Di Carlo, Valerio
AU - Zerbi, Alessandro
AU - Balzano, Gianpaolo
AU - Villa, Eugenio
PY - 1997/2
Y1 - 1997/2
N2 - In the 1985-1994 period, 101 patients underwent resection for ductal pancreatic adenocarcinoma. In 27 patients, the resection was not associated with adjuvant therapies, whereas in 74 patients, it was. Intraoperative radiation therapy (IORT) was performed in 54 patients. Operative mortality and morbidity were similar in patients undergoing IORT (1.8 and 29.6%) to those undergoing resection alone (2.1 and 27.6%). Median survival of the IORT group was 17 vs 14 mo of the non-IORT group (irrespective of postoperative treatments) (ns); the local recurrence rates were 38 and 54%, respectively. The group of 74 patients undergoing adjuvant therapies had a greater survival than 27 patients with no adjuvant treatment, both at the univariate (p
AB - In the 1985-1994 period, 101 patients underwent resection for ductal pancreatic adenocarcinoma. In 27 patients, the resection was not associated with adjuvant therapies, whereas in 74 patients, it was. Intraoperative radiation therapy (IORT) was performed in 54 patients. Operative mortality and morbidity were similar in patients undergoing IORT (1.8 and 29.6%) to those undergoing resection alone (2.1 and 27.6%). Median survival of the IORT group was 17 vs 14 mo of the non-IORT group (irrespective of postoperative treatments) (ns); the local recurrence rates were 38 and 54%, respectively. The group of 74 patients undergoing adjuvant therapies had a greater survival than 27 patients with no adjuvant treatment, both at the univariate (p
KW - chemotherapy
KW - external beam radiotherapy
KW - intraoperative radiation therapy
KW - Pancreatic cancer
KW - pancreatic resection
UR - http://www.scopus.com/inward/record.url?scp=0030997168&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030997168&partnerID=8YFLogxK
U2 - 10.1007/BF02785920
DO - 10.1007/BF02785920
M3 - Article
VL - 21
SP - 53
EP - 58
JO - International Journal of Gastrointestinal Cancer
JF - International Journal of Gastrointestinal Cancer
SN - 1537-3649
IS - 1
ER -