Intraoperative electron beam radiotherapy (ELIOT) to the breast: A need for a quality assurance programme

Roberto Orecchia, M. Ciocca, G. Tosi, S. Franzetti, A. Luini, G. Gatti, U. Veronesi

Research output: Contribution to journalArticlepeer-review


Intraoperative radiotherapy (IORT) is a technique in which a high, single-fraction radiation dose is delivered directly to the tumour bed during a surgical intervention, after the removal of a neoplastic mass. IORT has been recently used in early stage cancer as an exclusive radiation modality, rather than as a boost, especially for breast tumours, in particular at the European Institute of Oncology in Milan, where the technique has been called electron intraoperative therapy (ELIOT). Our studies on more than 1000 patients have demonstrated the feasibility of the technique and it is expected that its application will become more widespread in the immediate future. It is important to emphasise that ELIOT relies not only on new technological developments, but also on a multidisciplinary team with clear roles and responsibilities, the establishment of a programme of quality assurance with appropriate guidelines and a comprehensive staff development programme.

Original languageEnglish
Pages (from-to)541-546
Number of pages6
Issue number6
Publication statusPublished - Dec 2005


  • Breast cancer
  • In vivo dosimetry
  • Intraoperative radiation therapy
  • Mobile linear accelerator
  • Quality assurance

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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