Abstract
Intraoperative radiotherapy (IORT) has been used for many years for treating patients with various locally-advanced malignancies, usually combined with external-beam radiation therapy (EBRT). Long-term results confirm that IORT improves local control, which is generally associated with increased survival. Recently, electron-beam IORT has been used as the sole treatment for patients with earlier-stage cancers, especially for breast tumors, with extremely promising results. Most of this work has been done at the European Institute of Oncology in Milan. We report the rationale and techniques of the use of electron intraoperative treatment (ELIOT) and the results of our different clinical studies. In our opinion, ELIOT may be an excellent alternative to EBRT for the treatment of patients with early-stage breast cancer. However, intensive long-term follow-up is needed to fully evaluate local control and possible side effects.
| Original language | English |
|---|---|
| Pages (from-to) | 76-83 |
| Number of pages | 8 |
| Journal | Seminars in Radiation Oncology |
| Volume | 15 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Apr 2005 |
Fingerprint
ASJC Scopus subject areas
- Oncology
- Radiology Nuclear Medicine and imaging
- Radiological and Ultrasound Technology
- Radiation
Cite this
Intraoperative electrons. / Orecchia, Roberto; Veronesi, Umberto.
In: Seminars in Radiation Oncology, Vol. 15, No. 2, 04.2005, p. 76-83.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Intraoperative electrons
AU - Orecchia, Roberto
AU - Veronesi, Umberto
PY - 2005/4
Y1 - 2005/4
N2 - Intraoperative radiotherapy (IORT) has been used for many years for treating patients with various locally-advanced malignancies, usually combined with external-beam radiation therapy (EBRT). Long-term results confirm that IORT improves local control, which is generally associated with increased survival. Recently, electron-beam IORT has been used as the sole treatment for patients with earlier-stage cancers, especially for breast tumors, with extremely promising results. Most of this work has been done at the European Institute of Oncology in Milan. We report the rationale and techniques of the use of electron intraoperative treatment (ELIOT) and the results of our different clinical studies. In our opinion, ELIOT may be an excellent alternative to EBRT for the treatment of patients with early-stage breast cancer. However, intensive long-term follow-up is needed to fully evaluate local control and possible side effects.
AB - Intraoperative radiotherapy (IORT) has been used for many years for treating patients with various locally-advanced malignancies, usually combined with external-beam radiation therapy (EBRT). Long-term results confirm that IORT improves local control, which is generally associated with increased survival. Recently, electron-beam IORT has been used as the sole treatment for patients with earlier-stage cancers, especially for breast tumors, with extremely promising results. Most of this work has been done at the European Institute of Oncology in Milan. We report the rationale and techniques of the use of electron intraoperative treatment (ELIOT) and the results of our different clinical studies. In our opinion, ELIOT may be an excellent alternative to EBRT for the treatment of patients with early-stage breast cancer. However, intensive long-term follow-up is needed to fully evaluate local control and possible side effects.
UR - http://www.scopus.com/inward/record.url?scp=15944369669&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=15944369669&partnerID=8YFLogxK
U2 - 10.1016/j.semradonc.2004.10.009
DO - 10.1016/j.semradonc.2004.10.009
M3 - Article
C2 - 15809932
AN - SCOPUS:15944369669
VL - 15
SP - 76
EP - 83
JO - Seminars in Radiation Oncology
JF - Seminars in Radiation Oncology
SN - 1053-4296
IS - 2
ER -