Intraoperative electrons

Roberto Orecchia, Umberto Veronesi

Research output: Contribution to journalArticle

Abstract

Intraoperative radiotherapy (IORT) has been used for many years for treating patients with various locally-advanced malignancies, usually combined with external-beam radiation therapy (EBRT). Long-term results confirm that IORT improves local control, which is generally associated with increased survival. Recently, electron-beam IORT has been used as the sole treatment for patients with earlier-stage cancers, especially for breast tumors, with extremely promising results. Most of this work has been done at the European Institute of Oncology in Milan. We report the rationale and techniques of the use of electron intraoperative treatment (ELIOT) and the results of our different clinical studies. In our opinion, ELIOT may be an excellent alternative to EBRT for the treatment of patients with early-stage breast cancer. However, intensive long-term follow-up is needed to fully evaluate local control and possible side effects.

Original languageEnglish
Pages (from-to)76-83
Number of pages8
JournalSeminars in Radiation Oncology
Volume15
Issue number2
DOIs
Publication statusPublished - Apr 2005

Fingerprint

radiation therapy
Radiotherapy
Electrons
Breast Neoplasms
electrons
breast
cancer
Therapeutics
tumors
electron beams
Survival
Neoplasms

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Radiation

Cite this

Intraoperative electrons. / Orecchia, Roberto; Veronesi, Umberto.

In: Seminars in Radiation Oncology, Vol. 15, No. 2, 04.2005, p. 76-83.

Research output: Contribution to journalArticle

Orecchia, Roberto ; Veronesi, Umberto. / Intraoperative electrons. In: Seminars in Radiation Oncology. 2005 ; Vol. 15, No. 2. pp. 76-83.
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