Abstract
Background: Intraoperative radiotherapy with electrons allows the substitution of conventional postoperative whole breast irradiation with one session of radiotherapy with the same equivalent dose during surgery. However, its ability to control for recurrence of local disease required confirmation in a randomised controlled trial. Methods: This study was done at the European Institute of Oncology (Milan, Italy). Women aged 48-75 years with early breast cancer, a maximum tumour diameter of up to 2·5 cm, and suitable for breast-conserving surgery were randomly assigned in a 1:1 ratio (using a random permuted block design, stratified for clinical tumour size [
| Original language | English |
|---|---|
| Pages (from-to) | 1269-1277 |
| Number of pages | 9 |
| Journal | The Lancet Oncology |
| Volume | 14 |
| Issue number | 13 |
| DOIs | |
| Publication status | Published - Dec 2013 |
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ASJC Scopus subject areas
- Oncology
Cite this
Intraoperative radiotherapy versus external radiotherapy for early breast cancer (ELIOT) : A randomised controlled equivalence trial. / Veronesi, Umberto; Orecchia, Roberto; Maisonneuve, Patrick; Viale, Giuseppe; Rotmensz, Nicole; Sangalli, Claudia; Luini, Alberto; Veronesi, Paolo; Galimberti, Viviana; Zurrida, Stefano; Leonardi, Maria Cristina; Lazzari, Roberta; Cattani, Federica; Gentilini, Oreste; Intra, Mattia; Caldarella, Pietro; Ballardini, Bettina.
In: The Lancet Oncology, Vol. 14, No. 13, 12.2013, p. 1269-1277.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Intraoperative radiotherapy versus external radiotherapy for early breast cancer (ELIOT)
T2 - A randomised controlled equivalence trial
AU - Veronesi, Umberto
AU - Orecchia, Roberto
AU - Maisonneuve, Patrick
AU - Viale, Giuseppe
AU - Rotmensz, Nicole
AU - Sangalli, Claudia
AU - Luini, Alberto
AU - Veronesi, Paolo
AU - Galimberti, Viviana
AU - Zurrida, Stefano
AU - Leonardi, Maria Cristina
AU - Lazzari, Roberta
AU - Cattani, Federica
AU - Gentilini, Oreste
AU - Intra, Mattia
AU - Caldarella, Pietro
AU - Ballardini, Bettina
PY - 2013/12
Y1 - 2013/12
N2 - Background: Intraoperative radiotherapy with electrons allows the substitution of conventional postoperative whole breast irradiation with one session of radiotherapy with the same equivalent dose during surgery. However, its ability to control for recurrence of local disease required confirmation in a randomised controlled trial. Methods: This study was done at the European Institute of Oncology (Milan, Italy). Women aged 48-75 years with early breast cancer, a maximum tumour diameter of up to 2·5 cm, and suitable for breast-conserving surgery were randomly assigned in a 1:1 ratio (using a random permuted block design, stratified for clinical tumour size [
AB - Background: Intraoperative radiotherapy with electrons allows the substitution of conventional postoperative whole breast irradiation with one session of radiotherapy with the same equivalent dose during surgery. However, its ability to control for recurrence of local disease required confirmation in a randomised controlled trial. Methods: This study was done at the European Institute of Oncology (Milan, Italy). Women aged 48-75 years with early breast cancer, a maximum tumour diameter of up to 2·5 cm, and suitable for breast-conserving surgery were randomly assigned in a 1:1 ratio (using a random permuted block design, stratified for clinical tumour size [
UR - http://www.scopus.com/inward/record.url?scp=84888134506&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84888134506&partnerID=8YFLogxK
U2 - 10.1016/S1470-2045(13)70497-2
DO - 10.1016/S1470-2045(13)70497-2
M3 - Article
C2 - 24225155
AN - SCOPUS:84888134506
VL - 14
SP - 1269
EP - 1277
JO - The Lancet Oncology
JF - The Lancet Oncology
SN - 1470-2045
IS - 13
ER -