Intraoperative radiotherapy versus external radiotherapy for early breast cancer (ELIOT): A randomised controlled equivalence trial

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Abstract

Background: Intraoperative radiotherapy with electrons allows the substitution of conventional postoperative whole breast irradiation with one session of radiotherapy with the same equivalent dose during surgery. However, its ability to control for recurrence of local disease required confirmation in a randomised controlled trial. Methods: This study was done at the European Institute of Oncology (Milan, Italy). Women aged 48-75 years with early breast cancer, a maximum tumour diameter of up to 2·5 cm, and suitable for breast-conserving surgery were randomly assigned in a 1:1 ratio (using a random permuted block design, stratified for clinical tumour size [

Original languageEnglish
Pages (from-to)1269-1277
Number of pages9
JournalThe Lancet Oncology
Volume14
Issue number13
DOIs
Publication statusPublished - Dec 2013

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ASJC Scopus subject areas

  • Oncology

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