Intraoperative transfusion practices in Europe

J. Meier, D. Filipescu, S. Kozek-Langenecker, J. Llau Pitarch, S. Mallett, P. Martus, I. Matot, Giuseppe Accurso, Norbert Ahrens, Mert Akan, Kristin Åkeröy, Omur Aksoy, Zekeriyye Alanoğlu, Merten Alfredo, Neslihan Alkis, Valentina Almeida, Mohammed Alousi, Claudia Alves, Joana Amaral, Xavier AmbrosiIzquierdo Ana, Denisa Anastase, Mona Andersson, Antonis Andreou, Georgios Anthopoulos, Daiva Apanaviciute, Alejandro Arbelaez, Anne Laure Arcade, Carmen Arion-Balescu, Oguzhan Arun, Marta Azenha, Nicolae Bacalbasa, Wannes Baeten, Alina Balandin, Marta Barquero López, Victoria Barsan, Begona Bascuas, Misericordia Basora, Holger Baumann, Andreas Bayer, Andrea Bell, Julio Belmonte Cuenca, Zuleyha Kazak Bengisun, Carlos Bento, Maud Beran, Maria Bermudez Lopez, Ana Bernardino, Kasper Gymoese Berthelsen, Zekiye Bigat, Diana Bilshiene, Marcela Bilska, Elvira Bisbe Vives, Tamara Biscioni, Heyse Björn, Tommi Blom, Alexandru Bogdan Prodan, Matea Bogdanovic Dvorscak, Matthieu Boisson, Jens Bolten, Francesco Bona, Francis Borg, Cristian Boros, Michał Borys, Pierre Boveroux, Neval Boztug Uz, Florian Brettner, Laurent Brisard, De Waal Britta, Gail Browne, Kristin Budow, Hartmut Buerkle, Donal Buggy, Alistair Cain, Esenia Calancea, Florenta Calarasu, Verity Calder, Ali Emre Camci, Laura Campiglia, Beatriz Campos, Angela Camps, Delgado Carlos, Claudia Carreira, Alexandre Carrilho, Peter Carvalho, Concepcion Cassinello, Anat Cattan, Leonardo Cenni, Vladimir Cerny, Başak Ceyda Meço, Ion Chesov, Ahmed Chishti, Anne Marie Chupin, Andrea Cikova, Iulia Cindea, Daniel Cintula, Roxana Ciobanasu, Deborah Clements, Serghei Cobiletchi, Mark Coburn, Liz Coghlan, Thomas Collyer, Sanda Maria Copotoiu, Ruxandra Copotoiu, Dan Corneci, Andrea Cortegiani, O. Koray Coskunfirat, Dan Costea, Mirosław Czuczwar, Katy Davies, Luc De Baerdemaeker, Stefan De Hert, Felicino Debernardi, Sylvie Decagny, Nesil Deger Coskunfirat, Toma Diana, Gómez Martinez Diana, Sandra Dias, Matthew Dickinson, Anna Dobisova, Anca Dragan, Gabriela Droc, Sonia Duarte, Nigel Dunk, Kim Ekelund, Perihan Ekmekçi, Ciobanu Elena, Tracey Ellimah, Laura Espie, Lynn Everett, Andrew Ferguson, Melissa Fernandes, J. A. Fernández, Marion Ferner, Daniel Ferreira, Rosemary Ferrie, Daniela Filipescu, Zora Flassikova, Andreas Fleischer, A. Font, Katarina Galkova, Irene Garcia, Matt Garner, Andrey Gasenkampf, Arunas Gelmanas, Viorel Gherghina, Fernando Gilsanz, George Giokas, Ulrich Goebel, Piedade Gomes, José Manuel Gonçalves Aguiar, Veronica Gonzalez Monzon, André Gottschalk, Jean Pierre Gouraud, Elena Gramigni, Ioana Grintescu, Andriy Grynyuk, Alexey Grytsan, Emilia Guasch, Denis Gustin, Grégory Hans, Hana Harazim, Tore Hervig, Francisco Hidalgo, Charley Higham, Nicola Hirschauer, Andreas Hoeft, Petra Innerhofer, Nicole Innerhofer-Pompernigg, Stefan Jacobs, Nicolas Jakobs, Luc Jamaer, Sarah James, Monir Jawad, Joana Jesus, Shaman Jhanji, Nicoleta Jipa Lavina, Johanna Jokinen, Gordana Jovanovic, Maria Pilar Jubera, David Kahn, Juri Karjagin, Darja Kasnik, Konstantinos Katsanoulas, Hened Kelle, Mortimer Kelleher, Florian Kessler, Borana Kirigin, Olga Kiskira, Peeter Kivik, Pelagia Klimi, Jozef Klučka, Lena Koers, Egle Kontrimaviciut, A. W M M Koopman-Van Gemert, Demetrios Korfiotis, Martina Kosinová, Eygenia Koursoumi, Sibylle Kozek Langenecker, Peter Kranke, Marina Kresic, Renatas Krobot, Lucienne Kropman, Alexander Kulikov, Slavica Kvolik, Ivana Kvrgic, Aikaterini Kyttari, Filipa Lagarto, Marcus D. Lance, Rita Laufenberg, Severine Lauwick, Jean Pierre Lecoq, Leech Leech, Lionel Lidzborski, Henao Liliana, Filipe Linda, Juan Vicente Llau Pitarch, Ana Lopes, Luis Lopez, Alexo Lopez Alvarez, Irene Lorenzi, Gilbert Lorre, Horhota Lucian, Tamara Lupis, Mary Nicoleta Lupu, Andrius Macas, Ana Macedo, Genaro Maggi, Susan Mallett, Thomas Mallor, Alexandra Manoleli, Rely Manolescu, Susana Manrique, Isabelle Maquoi, Tasoulis Marios-Konstantinos, Jasmina Markovic Bozic, Hollmann W. Markus, Margarida Marques, Raul Martinez, Ever Martinez, Esther Martínez, Helder Martinho, Diogo Martins, Emilia Martires, Peter Martus, Francisco Matias, Idit Matot, Susanne Mauff, Paula Meale, Jens Meier, Hannah Merz, Patrick Meybohm, Maria Grazia Militello, Natalia Mincu, Maria Lina Miranda, Liliana Mirea, Victoria Moghildea, Alida Moise, Pablo Molano Diaz, Luís Moltó, Pablo Monedero, Victoria Moral, Zélia Moreira, Enrique Moret, Freya Mulders, Anna Maria Munteanu, Kinast Nadia Diana, Ashok Nair, Vojislava Neskovic, Vincent Ninane, Denisa Nitu, Dagmar Oberhofer, Suzanne Odeberg-Wernerman, Juri Oganjan, Dilek Omur, Marian Angeles Orallo Moran, Sevda Ozkardesler, Rita Pacasová, Nataša Paklar, Ageliki Pandazi, Fotios Papaspyros, Tilemachos Paraskeuopoulos, Suzana Parente, Marilena Alina Paunescu, Jadranka Pavičić Šarić, Filipa Pereira, Elizabete Pereira, Luciane Pereira, Chris Perry, Attila Petri, Uros Petrovic, Silvia Pica, Filipe Pinheiro, José Pinto, Fernando Pinto, Paweł Piwowarczyk, Sofie Platteau, Rita Poeira, Ravzan Popescu, Georgian Popica, Peter Poredos, Christopher Prasser, Benedikt Preckel, Audrey Prospiech, Roger Pujol, Ana Raimundo, Santi Maurizio Raineri, Dragana Rakic, Mohammed Ramadan, Atilla Ramazanoğlu, Athanasios Rantis, Ferrandis Raquel, Indrek Rätsep, Catia Real, Tore Reikvam, Ligia Reis, Jean Christophe Rigal, Anne Rohner, Alar Rokk, Adriana Roman Fernandez, Peter Rosenberger, Rolf Rossaint, Bertrand Rozec, Till Rudolph, Yousif Saeed, Sergej Safonov, Esra Saka, Charles Marc Samama, Óscar Sánchez López, David Sanchez Perez, Yvan Enrique Sanchez Sanchez, Varma Sandeep, Madalina Nina Sandu, Suat Sanll, Alexandra Saraiva, Ecaterina Scarlatescu, Renato Schiraldi, Gregor Schittek, Bettina Schnitter, Michael Schuster, Carlos Seco, Onur Selvi, Marc Senard, Sofia Serra, Helena Serrano, Alexander Shmigelsky, Luisa Silva, Karen Simeson, Rita Singh, Jurate Sipylaite, Kornel Skitek, Ira Skok, Olga Smékalová, Nadezda Smirnova, Machado Sofia, Maria Soler Pedrola, Sören Söndergaard, Alar Sõrmus, Ingvild Hausberg Sørvoll, Christos Soumelidis, Alenka Spindler Yesel, Mihai Stefan, Ana Stevanovic, Jordana Stevikova, Sabina Stivan, Petr Štourač, Jana Striteska, Lydia Strys, Ismet Suljevic, Moreno Tania, Gloria Tareco, Beatriz Tena, Kassiani Theodoraki, Marius Tifrea, Renatas Tikuisis, Raquel Tolós, Roland Tomasi, Dana Tomescu, Gabija Tomkute, Pilar Tormos, Darius Trepenaitis, Galina Troyan, Dragana Unic-Stojanovic, Axel Unterrainer, Jasna Uranjek, Dimitrios Valsamidis, Nick Van Dasselaar, Jurgen Van Limmen, Peter Van Noord, J. F. Van Poorten, Margot Vanderlaenen, Olalla Varela Garcia, Ana Velasco, Milic Veljovic, Jorge Vera Bella, Marcel Vercauteren, Bas Verdouw, Vladimir Verenkin, Tomas Veselovsky, Helena Vieira, Tania Villar, Ikic Visnja, Minca Voje, Vera Von Dossow-Hanfstingl, Daniel Von Langen, Sergiy Vorotyntsev, Vojislav Vujanovič, Rade Vukovic, Philip Watt, Eva Werner, Jan Wernerman, Maria Wittmann, Margaret Wright, Christian Wunder, Piet Wyffels, Yevgen Yakymenko, Çiğdem Ylldlrlm, Hakan Yllmaz, Kai Zacharowski, Roman Záhorec, Maged Zarif, Ewa Zielinska-Skitek, Lajos Zsisku

Research output: Contribution to journalArticle

Abstract

Background: Transfusion of allogeneic blood influences outcome after surgery. Despite widespread availability of transfusion guidelines, transfusion practices might vary among physicians, departments, hospitals and countries. Our aim was to determine the amount of packed red blood cells (pRBC) and blood products transfused intraoperatively, and to describe factors determining transfusion throughout Europe. Methods: We did a prospective observational cohort study enrolling 5803 patients in 126 European centres that received at least one pRBC unit intraoperatively, during a continuous three month period in 2013. Results: The overall intraoperative transfusion rate was 1.8%; 59% of transfusions were at least partially initiated as a result of a physiological transfusion trigger- mostly because of hypotension (55.4%) and/or tachycardia (30.7%). Haemoglobin (Hb)- based transfusion trigger alone initiated only 8.5% of transfusions. The Hb concentration [mean (sd)] just before transfusion was 8.1 (1.7) g dl-1 and increased to 9.8 (1.8) g dl-1 after transfusion. The mean number of intraoperatively transfused pRBC units was 2.5 (2.7) units (median 2). Conclusions: Although European Society of Anaesthesiology transfusion guidelines are moderately implemented in Europe with respect to Hb threshold for transfusion (7-9 g dl-1), there is still an urgent need for further educational efforts that focus on the number of pRBC units to be transfused at this threshold.

Original languageEnglish
Pages (from-to)255-261viii
JournalBritish Journal of Anaesthesia
Volume116
Issue number2
DOIs
Publication statusPublished - Feb 1 2016

Keywords

  • anaemia
  • anesthesia
  • blood transfusion
  • surgery
  • transfusion trigger

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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    Meier, J., Filipescu, D., Kozek-Langenecker, S., Llau Pitarch, J., Mallett, S., Martus, P., Matot, I., Accurso, G., Ahrens, N., Akan, M., Åkeröy, K., Aksoy, O., Alanoğlu, Z., Alfredo, M., Alkis, N., Almeida, V., Alousi, M., Alves, C., Amaral, J., ... Zsisku, L. (2016). Intraoperative transfusion practices in Europe. British Journal of Anaesthesia, 116(2), 255-261viii. https://doi.org/10.1093/bja/aev456