Abstract
Background: Transfusion of allogeneic blood influences outcome after surgery. Despite widespread availability of transfusion guidelines, transfusion practices might vary among physicians, departments, hospitals and countries. Our aim was to determine the amount of packed red blood cells (pRBC) and blood products transfused intraoperatively, and to describe factors determining transfusion throughout Europe. Methods: We did a prospective observational cohort study enrolling 5803 patients in 126 European centres that received at least one pRBC unit intraoperatively, during a continuous three month period in 2013. Results: The overall intraoperative transfusion rate was 1.8%; 59% of transfusions were at least partially initiated as a result of a physiological transfusion trigger- mostly because of hypotension (55.4%) and/or tachycardia (30.7%). Haemoglobin (Hb)- based transfusion trigger alone initiated only 8.5% of transfusions. The Hb concentration [mean (sd)] just before transfusion was 8.1 (1.7) g dl-1 and increased to 9.8 (1.8) g dl-1 after transfusion. The mean number of intraoperatively transfused pRBC units was 2.5 (2.7) units (median 2). Conclusions: Although European Society of Anaesthesiology transfusion guidelines are moderately implemented in Europe with respect to Hb threshold for transfusion (7-9 g dl-1), there is still an urgent need for further educational efforts that focus on the number of pRBC units to be transfused at this threshold.
| Original language | English |
|---|---|
| Pages (from-to) | 255-261viii |
| Journal | British Journal of Anaesthesia |
| Volume | 116 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Feb 1 2016 |
Keywords
- anaemia
- anesthesia
- blood transfusion
- surgery
- transfusion trigger
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine
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Intraoperative transfusion practices in Europe. / Meier, J.; Filipescu, D.; Kozek-Langenecker, S.; Llau Pitarch, J.; Mallett, S.; Martus, P.; Matot, I.; Accurso, Giuseppe; Ahrens, Norbert; Akan, Mert; Åkeröy, Kristin; Aksoy, Omur; Alanoğlu, Zekeriyye; Alfredo, Merten; Alkis, Neslihan; Almeida, Valentina; Alousi, Mohammed; Alves, Claudia; Amaral, Joana; Ambrosi, Xavier; Ana, Izquierdo; Anastase, Denisa; Andersson, Mona; Andreou, Antonis; Anthopoulos, Georgios; Apanaviciute, Daiva; Arbelaez, Alejandro; Arcade, Anne Laure; Arion-Balescu, Carmen; Arun, Oguzhan; Azenha, Marta; Bacalbasa, Nicolae; Baeten, Wannes; Balandin, Alina; Barquero López, Marta; Barsan, Victoria; Bascuas, Begona; Basora, Misericordia; Baumann, Holger; Bayer, Andreas; Bell, Andrea; Belmonte Cuenca, Julio; Bengisun, Zuleyha Kazak; Bento, Carlos; Beran, Maud; Bermudez Lopez, Maria; Bernardino, Ana; Berthelsen, Kasper Gymoese; Bigat, Zekiye; Bilshiene, Diana; Bilska, Marcela; Bisbe Vives, Elvira; Biscioni, Tamara; Björn, Heyse; Blom, Tommi; Bogdan Prodan, Alexandru; Bogdanovic Dvorscak, Matea; Boisson, Matthieu; Bolten, Jens; Bona, Francesco; Borg, Francis; Boros, Cristian; Borys, Michał; Boveroux, Pierre; Boztug Uz, Neval; Brettner, Florian; Brisard, Laurent; Britta, De Waal; Browne, Gail; Budow, Kristin; Buerkle, Hartmut; Buggy, Donal; Cain, Alistair; Calancea, Esenia; Calarasu, Florenta; Calder, Verity; Camci, Ali Emre; Campiglia, Laura; Campos, Beatriz; Camps, Angela; Carlos, Delgado; Carreira, Claudia; Carrilho, Alexandre; Carvalho, Peter; Cassinello, Concepcion; Cattan, Anat; Cenni, Leonardo; Cerny, Vladimir; Ceyda Meço, Başak; Chesov, Ion; Chishti, Ahmed; Chupin, Anne Marie; Cikova, Andrea; Cindea, Iulia; Cintula, Daniel; Ciobanasu, Roxana; Clements, Deborah; Cobiletchi, Serghei; Coburn, Mark; Coghlan, Liz; Collyer, Thomas; Copotoiu, Sanda Maria; Copotoiu, Ruxandra; Corneci, Dan; Cortegiani, Andrea; Coskunfirat, O. Koray; Costea, Dan; Czuczwar, Mirosław; Davies, Katy; De Baerdemaeker, Luc; De Hert, Stefan; Debernardi, Felicino; Decagny, Sylvie; Deger Coskunfirat, Nesil; Diana, Toma; Diana, Gómez Martinez; Dias, Sandra; Dickinson, Matthew; Dobisova, Anna; Dragan, Anca; Droc, Gabriela; Duarte, Sonia; Dunk, Nigel; Ekelund, Kim; Ekmekçi, Perihan; Elena, Ciobanu; Ellimah, Tracey; Espie, Laura; Everett, Lynn; Ferguson, Andrew; Fernandes, Melissa; Fernández, J. A.; Ferner, Marion; Ferreira, Daniel; Ferrie, Rosemary; Filipescu, Daniela; Flassikova, Zora; Fleischer, Andreas; Font, A.; Galkova, Katarina; Garcia, Irene; Garner, Matt; Gasenkampf, Andrey; Gelmanas, Arunas; Gherghina, Viorel; Gilsanz, Fernando; Giokas, George; Goebel, Ulrich; Gomes, Piedade; Gonçalves Aguiar, José Manuel; Gonzalez Monzon, Veronica; Gottschalk, André; Gouraud, Jean Pierre; Gramigni, Elena; Grintescu, Ioana; Grynyuk, Andriy; Grytsan, Alexey; Guasch, Emilia; Gustin, Denis; Hans, Grégory; Harazim, Hana; Hervig, Tore; Hidalgo, Francisco; Higham, Charley; Hirschauer, Nicola; Hoeft, Andreas; Innerhofer, Petra; Innerhofer-Pompernigg, Nicole; Jacobs, Stefan; Jakobs, Nicolas; Jamaer, Luc; James, Sarah; Jawad, Monir; Jesus, Joana; Jhanji, Shaman; Jipa Lavina, Nicoleta; Jokinen, Johanna; Jovanovic, Gordana; Jubera, Maria Pilar; Kahn, David; Karjagin, Juri; Kasnik, Darja; Katsanoulas, Konstantinos; Kelle, Hened; Kelleher, Mortimer; Kessler, Florian; Kirigin, Borana; Kiskira, Olga; Kivik, Peeter; Klimi, Pelagia; Klučka, Jozef; Koers, Lena; Kontrimaviciut, Egle; Koopman-Van Gemert, A. W M M; Korfiotis, Demetrios; Kosinová, Martina; Koursoumi, Eygenia; Kozek Langenecker, Sibylle; Kranke, Peter; Kresic, Marina; Krobot, Renatas; Kropman, Lucienne; Kulikov, Alexander; Kvolik, Slavica; Kvrgic, Ivana; Kyttari, Aikaterini; Lagarto, Filipa; Lance, Marcus D.; Laufenberg, Rita; Lauwick, Severine; Lecoq, Jean Pierre; Leech, Leech; Lidzborski, Lionel; Liliana, Henao; Linda, Filipe; Llau Pitarch, Juan Vicente; Lopes, Ana; Lopez, Luis; Lopez Alvarez, Alexo; Lorenzi, Irene; Lorre, Gilbert; Lucian, Horhota; Lupis, Tamara; Lupu, Mary Nicoleta; Macas, Andrius; Macedo, Ana; Maggi, Genaro; Mallett, Susan; Mallor, Thomas; Manoleli, Alexandra; Manolescu, Rely; Manrique, Susana; Maquoi, Isabelle; Marios-Konstantinos, Tasoulis; Markovic Bozic, Jasmina; Markus, Hollmann W.; Marques, Margarida; Martinez, Raul; Martinez, Ever; Martínez, Esther; Martinho, Helder; Martins, Diogo; Martires, Emilia; Martus, Peter; Matias, Francisco; Matot, Idit; Mauff, Susanne; Meale, Paula; Meier, Jens; Merz, Hannah; Meybohm, Patrick; Militello, Maria Grazia; Mincu, Natalia; Miranda, Maria Lina; Mirea, Liliana; Moghildea, Victoria; Moise, Alida; Molano Diaz, Pablo; Moltó, Luís; Monedero, Pablo; Moral, Victoria; Moreira, Zélia; Moret, Enrique; Mulders, Freya; Munteanu, Anna Maria; Nadia Diana, Kinast; Nair, Ashok; Neskovic, Vojislava; Ninane, Vincent; Nitu, Denisa; Oberhofer, Dagmar; Odeberg-Wernerman, Suzanne; Oganjan, Juri; Omur, Dilek; Orallo Moran, Marian Angeles; Ozkardesler, Sevda; Pacasová, Rita; Paklar, Nataša; Pandazi, Ageliki; Papaspyros, Fotios; Paraskeuopoulos, Tilemachos; Parente, Suzana; Paunescu, Marilena Alina; Pavičić Šarić, Jadranka; Pereira, Filipa; Pereira, Elizabete; Pereira, Luciane; Perry, Chris; Petri, Attila; Petrovic, Uros; Pica, Silvia; Pinheiro, Filipe; Pinto, José; Pinto, Fernando; Piwowarczyk, Paweł; Platteau, Sofie; Poeira, Rita; Popescu, Ravzan; Popica, Georgian; Poredos, Peter; Prasser, Christopher; Preckel, Benedikt; Prospiech, Audrey; Pujol, Roger; Raimundo, Ana; Raineri, Santi Maurizio; Rakic, Dragana; Ramadan, Mohammed; Ramazanoğlu, Atilla; Rantis, Athanasios; Raquel, Ferrandis; Rätsep, Indrek; Real, Catia; Reikvam, Tore; Reis, Ligia; Rigal, Jean Christophe; Rohner, Anne; Rokk, Alar; Roman Fernandez, Adriana; Rosenberger, Peter; Rossaint, Rolf; Rozec, Bertrand; Rudolph, Till; Saeed, Yousif; Safonov, Sergej; Saka, Esra; Samama, Charles Marc; Sánchez López, Óscar; Sanchez Perez, David; Sanchez Sanchez, Yvan Enrique; Sandeep, Varma; Sandu, Madalina Nina; Sanll, Suat; Saraiva, Alexandra; Scarlatescu, Ecaterina; Schiraldi, Renato; Schittek, Gregor; Schnitter, Bettina; Schuster, Michael; Seco, Carlos; Selvi, Onur; Senard, Marc; Serra, Sofia; Serrano, Helena; Shmigelsky, Alexander; Silva, Luisa; Simeson, Karen; Singh, Rita; Sipylaite, Jurate; Skitek, Kornel; Skok, Ira; Smékalová, Olga; Smirnova, Nadezda; Sofia, Machado; Soler Pedrola, Maria; Söndergaard, Sören; Sõrmus, Alar; Sørvoll, Ingvild Hausberg; Soumelidis, Christos; Spindler Yesel, Alenka; Stefan, Mihai; Stevanovic, Ana; Stevikova, Jordana; Stivan, Sabina; Štourač, Petr; Striteska, Jana; Strys, Lydia; Suljevic, Ismet; Tania, Moreno; Tareco, Gloria; Tena, Beatriz; Theodoraki, Kassiani; Tifrea, Marius; Tikuisis, Renatas; Tolós, Raquel; Tomasi, Roland; Tomescu, Dana; Tomkute, Gabija; Tormos, Pilar; Trepenaitis, Darius; Troyan, Galina; Unic-Stojanovic, Dragana; Unterrainer, Axel; Uranjek, Jasna; Valsamidis, Dimitrios; Van Dasselaar, Nick; Van Limmen, Jurgen; Van Noord, Peter; Van Poorten, J. F.; Vanderlaenen, Margot; Varela Garcia, Olalla; Velasco, Ana; Veljovic, Milic; Vera Bella, Jorge; Vercauteren, Marcel; Verdouw, Bas; Verenkin, Vladimir; Veselovsky, Tomas; Vieira, Helena; Villar, Tania; Visnja, Ikic; Voje, Minca; Von Dossow-Hanfstingl, Vera; Von Langen, Daniel; Vorotyntsev, Sergiy; Vujanovič, Vojislav; Vukovic, Rade; Watt, Philip; Werner, Eva; Wernerman, Jan; Wittmann, Maria; Wright, Margaret; Wunder, Christian; Wyffels, Piet; Yakymenko, Yevgen; Ylldlrlm, Çiğdem; Yllmaz, Hakan; Zacharowski, Kai; Záhorec, Roman; Zarif, Maged; Zielinska-Skitek, Ewa; Zsisku, Lajos.
In: British Journal of Anaesthesia, Vol. 116, No. 2, 01.02.2016, p. 255-261viii.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Intraoperative transfusion practices in Europe
AU - Meier, J.
AU - Filipescu, D.
AU - Kozek-Langenecker, S.
AU - Llau Pitarch, J.
AU - Mallett, S.
AU - Martus, P.
AU - Matot, I.
AU - Accurso, Giuseppe
AU - Ahrens, Norbert
AU - Akan, Mert
AU - Åkeröy, Kristin
AU - Aksoy, Omur
AU - Alanoğlu, Zekeriyye
AU - Alfredo, Merten
AU - Alkis, Neslihan
AU - Almeida, Valentina
AU - Alousi, Mohammed
AU - Alves, Claudia
AU - Amaral, Joana
AU - Ambrosi, Xavier
AU - Ana, Izquierdo
AU - Anastase, Denisa
AU - Andersson, Mona
AU - Andreou, Antonis
AU - Anthopoulos, Georgios
AU - Apanaviciute, Daiva
AU - Arbelaez, Alejandro
AU - Arcade, Anne Laure
AU - Arion-Balescu, Carmen
AU - Arun, Oguzhan
AU - Azenha, Marta
AU - Bacalbasa, Nicolae
AU - Baeten, Wannes
AU - Balandin, Alina
AU - Barquero López, Marta
AU - Barsan, Victoria
AU - Bascuas, Begona
AU - Basora, Misericordia
AU - Baumann, Holger
AU - Bayer, Andreas
AU - Bell, Andrea
AU - Belmonte Cuenca, Julio
AU - Bengisun, Zuleyha Kazak
AU - Bento, Carlos
AU - Beran, Maud
AU - Bermudez Lopez, Maria
AU - Bernardino, Ana
AU - Berthelsen, Kasper Gymoese
AU - Bigat, Zekiye
AU - Bilshiene, Diana
AU - Bilska, Marcela
AU - Bisbe Vives, Elvira
AU - Biscioni, Tamara
AU - Björn, Heyse
AU - Blom, Tommi
AU - Bogdan Prodan, Alexandru
AU - Bogdanovic Dvorscak, Matea
AU - Boisson, Matthieu
AU - Bolten, Jens
AU - Bona, Francesco
AU - Borg, Francis
AU - Boros, Cristian
AU - Borys, Michał
AU - Boveroux, Pierre
AU - Boztug Uz, Neval
AU - Brettner, Florian
AU - Brisard, Laurent
AU - Britta, De Waal
AU - Browne, Gail
AU - Budow, Kristin
AU - Buerkle, Hartmut
AU - Buggy, Donal
AU - Cain, Alistair
AU - Calancea, Esenia
AU - Calarasu, Florenta
AU - Calder, Verity
AU - Camci, Ali Emre
AU - Campiglia, Laura
AU - Campos, Beatriz
AU - Camps, Angela
AU - Carlos, Delgado
AU - Carreira, Claudia
AU - Carrilho, Alexandre
AU - Carvalho, Peter
AU - Cassinello, Concepcion
AU - Cattan, Anat
AU - Cenni, Leonardo
AU - Cerny, Vladimir
AU - Ceyda Meço, Başak
AU - Chesov, Ion
AU - Chishti, Ahmed
AU - Chupin, Anne Marie
AU - Cikova, Andrea
AU - Cindea, Iulia
AU - Cintula, Daniel
AU - Ciobanasu, Roxana
AU - Clements, Deborah
AU - Cobiletchi, Serghei
AU - Coburn, Mark
AU - Coghlan, Liz
AU - Collyer, Thomas
AU - Copotoiu, Sanda Maria
AU - Copotoiu, Ruxandra
AU - Corneci, Dan
AU - Cortegiani, Andrea
AU - Coskunfirat, O. Koray
AU - Costea, Dan
AU - Czuczwar, Mirosław
AU - Davies, Katy
AU - De Baerdemaeker, Luc
AU - De Hert, Stefan
AU - Debernardi, Felicino
AU - Decagny, Sylvie
AU - Deger Coskunfirat, Nesil
AU - Diana, Toma
AU - Diana, Gómez Martinez
AU - Dias, Sandra
AU - Dickinson, Matthew
AU - Dobisova, Anna
AU - Dragan, Anca
AU - Droc, Gabriela
AU - Duarte, Sonia
AU - Dunk, Nigel
AU - Ekelund, Kim
AU - Ekmekçi, Perihan
AU - Elena, Ciobanu
AU - Ellimah, Tracey
AU - Espie, Laura
AU - Everett, Lynn
AU - Ferguson, Andrew
AU - Fernandes, Melissa
AU - Fernández, J. A.
AU - Ferner, Marion
AU - Ferreira, Daniel
AU - Ferrie, Rosemary
AU - Filipescu, Daniela
AU - Flassikova, Zora
AU - Fleischer, Andreas
AU - Font, A.
AU - Galkova, Katarina
AU - Garcia, Irene
AU - Garner, Matt
AU - Gasenkampf, Andrey
AU - Gelmanas, Arunas
AU - Gherghina, Viorel
AU - Gilsanz, Fernando
AU - Giokas, George
AU - Goebel, Ulrich
AU - Gomes, Piedade
AU - Gonçalves Aguiar, José Manuel
AU - Gonzalez Monzon, Veronica
AU - Gottschalk, André
AU - Gouraud, Jean Pierre
AU - Gramigni, Elena
AU - Grintescu, Ioana
AU - Grynyuk, Andriy
AU - Grytsan, Alexey
AU - Guasch, Emilia
AU - Gustin, Denis
AU - Hans, Grégory
AU - Harazim, Hana
AU - Hervig, Tore
AU - Hidalgo, Francisco
AU - Higham, Charley
AU - Hirschauer, Nicola
AU - Hoeft, Andreas
AU - Innerhofer, Petra
AU - Innerhofer-Pompernigg, Nicole
AU - Jacobs, Stefan
AU - Jakobs, Nicolas
AU - Jamaer, Luc
AU - James, Sarah
AU - Jawad, Monir
AU - Jesus, Joana
AU - Jhanji, Shaman
AU - Jipa Lavina, Nicoleta
AU - Jokinen, Johanna
AU - Jovanovic, Gordana
AU - Jubera, Maria Pilar
AU - Kahn, David
AU - Karjagin, Juri
AU - Kasnik, Darja
AU - Katsanoulas, Konstantinos
AU - Kelle, Hened
AU - Kelleher, Mortimer
AU - Kessler, Florian
AU - Kirigin, Borana
AU - Kiskira, Olga
AU - Kivik, Peeter
AU - Klimi, Pelagia
AU - Klučka, Jozef
AU - Koers, Lena
AU - Kontrimaviciut, Egle
AU - Koopman-Van Gemert, A. W M M
AU - Korfiotis, Demetrios
AU - Kosinová, Martina
AU - Koursoumi, Eygenia
AU - Kozek Langenecker, Sibylle
AU - Kranke, Peter
AU - Kresic, Marina
AU - Krobot, Renatas
AU - Kropman, Lucienne
AU - Kulikov, Alexander
AU - Kvolik, Slavica
AU - Kvrgic, Ivana
AU - Kyttari, Aikaterini
AU - Lagarto, Filipa
AU - Lance, Marcus D.
AU - Laufenberg, Rita
AU - Lauwick, Severine
AU - Lecoq, Jean Pierre
AU - Leech, Leech
AU - Lidzborski, Lionel
AU - Liliana, Henao
AU - Linda, Filipe
AU - Llau Pitarch, Juan Vicente
AU - Lopes, Ana
AU - Lopez, Luis
AU - Lopez Alvarez, Alexo
AU - Lorenzi, Irene
AU - Lorre, Gilbert
AU - Lucian, Horhota
AU - Lupis, Tamara
AU - Lupu, Mary Nicoleta
AU - Macas, Andrius
AU - Macedo, Ana
AU - Maggi, Genaro
AU - Mallett, Susan
AU - Mallor, Thomas
AU - Manoleli, Alexandra
AU - Manolescu, Rely
AU - Manrique, Susana
AU - Maquoi, Isabelle
AU - Marios-Konstantinos, Tasoulis
AU - Markovic Bozic, Jasmina
AU - Markus, Hollmann W.
AU - Marques, Margarida
AU - Martinez, Raul
AU - Martinez, Ever
AU - Martínez, Esther
AU - Martinho, Helder
AU - Martins, Diogo
AU - Martires, Emilia
AU - Martus, Peter
AU - Matias, Francisco
AU - Matot, Idit
AU - Mauff, Susanne
AU - Meale, Paula
AU - Meier, Jens
AU - Merz, Hannah
AU - Meybohm, Patrick
AU - Militello, Maria Grazia
AU - Mincu, Natalia
AU - Miranda, Maria Lina
AU - Mirea, Liliana
AU - Moghildea, Victoria
AU - Moise, Alida
AU - Molano Diaz, Pablo
AU - Moltó, Luís
AU - Monedero, Pablo
AU - Moral, Victoria
AU - Moreira, Zélia
AU - Moret, Enrique
AU - Mulders, Freya
AU - Munteanu, Anna Maria
AU - Nadia Diana, Kinast
AU - Nair, Ashok
AU - Neskovic, Vojislava
AU - Ninane, Vincent
AU - Nitu, Denisa
AU - Oberhofer, Dagmar
AU - Odeberg-Wernerman, Suzanne
AU - Oganjan, Juri
AU - Omur, Dilek
AU - Orallo Moran, Marian Angeles
AU - Ozkardesler, Sevda
AU - Pacasová, Rita
AU - Paklar, Nataša
AU - Pandazi, Ageliki
AU - Papaspyros, Fotios
AU - Paraskeuopoulos, Tilemachos
AU - Parente, Suzana
AU - Paunescu, Marilena Alina
AU - Pavičić Šarić, Jadranka
AU - Pereira, Filipa
AU - Pereira, Elizabete
AU - Pereira, Luciane
AU - Perry, Chris
AU - Petri, Attila
AU - Petrovic, Uros
AU - Pica, Silvia
AU - Pinheiro, Filipe
AU - Pinto, José
AU - Pinto, Fernando
AU - Piwowarczyk, Paweł
AU - Platteau, Sofie
AU - Poeira, Rita
AU - Popescu, Ravzan
AU - Popica, Georgian
AU - Poredos, Peter
AU - Prasser, Christopher
AU - Preckel, Benedikt
AU - Prospiech, Audrey
AU - Pujol, Roger
AU - Raimundo, Ana
AU - Raineri, Santi Maurizio
AU - Rakic, Dragana
AU - Ramadan, Mohammed
AU - Ramazanoğlu, Atilla
AU - Rantis, Athanasios
AU - Raquel, Ferrandis
AU - Rätsep, Indrek
AU - Real, Catia
AU - Reikvam, Tore
AU - Reis, Ligia
AU - Rigal, Jean Christophe
AU - Rohner, Anne
AU - Rokk, Alar
AU - Roman Fernandez, Adriana
AU - Rosenberger, Peter
AU - Rossaint, Rolf
AU - Rozec, Bertrand
AU - Rudolph, Till
AU - Saeed, Yousif
AU - Safonov, Sergej
AU - Saka, Esra
AU - Samama, Charles Marc
AU - Sánchez López, Óscar
AU - Sanchez Perez, David
AU - Sanchez Sanchez, Yvan Enrique
AU - Sandeep, Varma
AU - Sandu, Madalina Nina
AU - Sanll, Suat
AU - Saraiva, Alexandra
AU - Scarlatescu, Ecaterina
AU - Schiraldi, Renato
AU - Schittek, Gregor
AU - Schnitter, Bettina
AU - Schuster, Michael
AU - Seco, Carlos
AU - Selvi, Onur
AU - Senard, Marc
AU - Serra, Sofia
AU - Serrano, Helena
AU - Shmigelsky, Alexander
AU - Silva, Luisa
AU - Simeson, Karen
AU - Singh, Rita
AU - Sipylaite, Jurate
AU - Skitek, Kornel
AU - Skok, Ira
AU - Smékalová, Olga
AU - Smirnova, Nadezda
AU - Sofia, Machado
AU - Soler Pedrola, Maria
AU - Söndergaard, Sören
AU - Sõrmus, Alar
AU - Sørvoll, Ingvild Hausberg
AU - Soumelidis, Christos
AU - Spindler Yesel, Alenka
AU - Stefan, Mihai
AU - Stevanovic, Ana
AU - Stevikova, Jordana
AU - Stivan, Sabina
AU - Štourač, Petr
AU - Striteska, Jana
AU - Strys, Lydia
AU - Suljevic, Ismet
AU - Tania, Moreno
AU - Tareco, Gloria
AU - Tena, Beatriz
AU - Theodoraki, Kassiani
AU - Tifrea, Marius
AU - Tikuisis, Renatas
AU - Tolós, Raquel
AU - Tomasi, Roland
AU - Tomescu, Dana
AU - Tomkute, Gabija
AU - Tormos, Pilar
AU - Trepenaitis, Darius
AU - Troyan, Galina
AU - Unic-Stojanovic, Dragana
AU - Unterrainer, Axel
AU - Uranjek, Jasna
AU - Valsamidis, Dimitrios
AU - Van Dasselaar, Nick
AU - Van Limmen, Jurgen
AU - Van Noord, Peter
AU - Van Poorten, J. F.
AU - Vanderlaenen, Margot
AU - Varela Garcia, Olalla
AU - Velasco, Ana
AU - Veljovic, Milic
AU - Vera Bella, Jorge
AU - Vercauteren, Marcel
AU - Verdouw, Bas
AU - Verenkin, Vladimir
AU - Veselovsky, Tomas
AU - Vieira, Helena
AU - Villar, Tania
AU - Visnja, Ikic
AU - Voje, Minca
AU - Von Dossow-Hanfstingl, Vera
AU - Von Langen, Daniel
AU - Vorotyntsev, Sergiy
AU - Vujanovič, Vojislav
AU - Vukovic, Rade
AU - Watt, Philip
AU - Werner, Eva
AU - Wernerman, Jan
AU - Wittmann, Maria
AU - Wright, Margaret
AU - Wunder, Christian
AU - Wyffels, Piet
AU - Yakymenko, Yevgen
AU - Ylldlrlm, Çiğdem
AU - Yllmaz, Hakan
AU - Zacharowski, Kai
AU - Záhorec, Roman
AU - Zarif, Maged
AU - Zielinska-Skitek, Ewa
AU - Zsisku, Lajos
PY - 2016/2/1
Y1 - 2016/2/1
N2 - Background: Transfusion of allogeneic blood influences outcome after surgery. Despite widespread availability of transfusion guidelines, transfusion practices might vary among physicians, departments, hospitals and countries. Our aim was to determine the amount of packed red blood cells (pRBC) and blood products transfused intraoperatively, and to describe factors determining transfusion throughout Europe. Methods: We did a prospective observational cohort study enrolling 5803 patients in 126 European centres that received at least one pRBC unit intraoperatively, during a continuous three month period in 2013. Results: The overall intraoperative transfusion rate was 1.8%; 59% of transfusions were at least partially initiated as a result of a physiological transfusion trigger- mostly because of hypotension (55.4%) and/or tachycardia (30.7%). Haemoglobin (Hb)- based transfusion trigger alone initiated only 8.5% of transfusions. The Hb concentration [mean (sd)] just before transfusion was 8.1 (1.7) g dl-1 and increased to 9.8 (1.8) g dl-1 after transfusion. The mean number of intraoperatively transfused pRBC units was 2.5 (2.7) units (median 2). Conclusions: Although European Society of Anaesthesiology transfusion guidelines are moderately implemented in Europe with respect to Hb threshold for transfusion (7-9 g dl-1), there is still an urgent need for further educational efforts that focus on the number of pRBC units to be transfused at this threshold.
AB - Background: Transfusion of allogeneic blood influences outcome after surgery. Despite widespread availability of transfusion guidelines, transfusion practices might vary among physicians, departments, hospitals and countries. Our aim was to determine the amount of packed red blood cells (pRBC) and blood products transfused intraoperatively, and to describe factors determining transfusion throughout Europe. Methods: We did a prospective observational cohort study enrolling 5803 patients in 126 European centres that received at least one pRBC unit intraoperatively, during a continuous three month period in 2013. Results: The overall intraoperative transfusion rate was 1.8%; 59% of transfusions were at least partially initiated as a result of a physiological transfusion trigger- mostly because of hypotension (55.4%) and/or tachycardia (30.7%). Haemoglobin (Hb)- based transfusion trigger alone initiated only 8.5% of transfusions. The Hb concentration [mean (sd)] just before transfusion was 8.1 (1.7) g dl-1 and increased to 9.8 (1.8) g dl-1 after transfusion. The mean number of intraoperatively transfused pRBC units was 2.5 (2.7) units (median 2). Conclusions: Although European Society of Anaesthesiology transfusion guidelines are moderately implemented in Europe with respect to Hb threshold for transfusion (7-9 g dl-1), there is still an urgent need for further educational efforts that focus on the number of pRBC units to be transfused at this threshold.
KW - anaemia
KW - anesthesia
KW - blood transfusion
KW - surgery
KW - transfusion trigger
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U2 - 10.1093/bja/aev456
DO - 10.1093/bja/aev456
M3 - Article
AN - SCOPUS:84961917688
VL - 116
SP - 255-261viii
JO - British Journal of Anaesthesia
JF - British Journal of Anaesthesia
SN - 0007-0912
IS - 2
ER -