Intrastromal perioptic implants for the correction of high myopia: Biologic and biomechanical evaluation

C. Bisantis, E. Midena, S. Patel, F. Provenzano, F. Bisantis, A. Mancini

Research output: Contribution to journalArticlepeer-review


Purpose. To study the biologic and biomechanical effects of intrastromal perioptic implants (ISPI) for the correction of high myopia. Methods. 38 eyes affected by high myopia (>12) under vent implantation of intrastromal PMMA ( polymethyimethacrylate) perioptic implants according to our technique ( IOVS 36:S988, 1995). 4 PMMA segments (250 μ in thickness) were implanted using different optic zones ( 3 to 5 mm) depending on the degree of myopia. Refraction, corneal parameters and corneal signs and symptoms related to implantation were reported at 1, 30, 90, 180 and 360 days after the operation. Results. Early postoperative reduction of myopic refraction was 15.14 ± 4.46 diopters. In 45% of the patients we observed late extrusion of the implants with return to preoperative status after healing. 2 eyes had keratitis which healed with antibiotics eyedrops. Average change in ocular surface power was lower than in ocular refraction (-9.8 vs -14.7, p<05). Change in corneal surface power was much greater than that predicted by simple segments insertion. Conclusions. ISPI is a new safe, reversible but stil unpredictable technique for the correction of high myopia. A flattening of the posterior surface of the cornea and steepening of the boundary betweer the epithelium and anterior stroma may affect post operative final refraction.

Original languageEnglish
JournalInvestigative Ophthalmology and Visual Science
Issue number3
Publication statusPublished - Feb 15 1996

ASJC Scopus subject areas

  • Ophthalmology


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