Intrasurgical use of steroids on carpal tunnel syndrome: A randomized, prospective, double-blind controlled study

R. Padua, L. Padua, R. Bondì, A. Campi, E. Ceccarelli, S. Padua

Research output: Contribution to journalArticle


We studied steroid irrigation of the median nerve during surgical decompression in carpal tunnel syndrome through a prospective randomized controlled study. After sample size calculation, 20 patients were randomized into two groups: one group had a release of the transverse carpal ligament alone, and the other one had a release associated with steroid irrigation of the median nerve. The patients were evaluated preoperatively and postoperatively at 15 days and 2 months through a widely used and validated patient-oriented measure (the Carpal tunnel questionnaire) and through neurophysiological evaluation. The follow-up assessment showed significant differences in the postoperative evolution between the two groups with regard to symptoms: symptoms were less in the steroid-treated group both at 15 days (p>0.035; z=-2.9) and at two months (p

Original languageEnglish
Pages (from-to)76-80
Number of pages5
JournalJournal of Orthopaedics and Traumatology
Issue number2
Publication statusPublished - Aug 2003



  • Carpal tunnel questionnaire
  • Carpal tunnel syndrome
  • Neurophysiologic evaluation
  • Randomized controlled trial
  • Steroids

ASJC Scopus subject areas

  • Surgery

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