Intrathecal baclofen treatment of severe spasticity in MS patients

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The administration of intrathecal baclofen has proven to be effective in the treatment of severe spasticity. The effects of baclofen have been described in all types of spinal spasticity, even in multiple sclerosis: effects on the spasms, on the hypertone and on the hyperreflexia. In this study we report on 14 polysclerotic patients, suffering from severe spinal spasticity, undergoing chronic intrathecal baclofen treatment with the use of computerized pump, that permits the continuous or intermittent release of dosages much lower that dose used orally. The results obtained show a notable reduction in spastic symptomatology with an improvement of the voluntary motor functions in some cases. Our observations confirm the validity of intrathecal baclofen even in the symptomatic therapy of multiple sclerosis.

Original languageEnglish
Pages (from-to)119
Number of pages1
JournalItalian Journal of Neurological Sciences
Issue number4
Publication statusPublished - 1997

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


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