Intravascular Ultrasound Assessment of Ulcerated Ruptured Plaques: A Comparison of Culprit and Nonculprit Lesions of Patients with Acute Coronary Syndromes and Lesions in Patients Without Acute Coronary Syndromes

Kenichi Fujii, Yoshio Kobayashi, Gary S. Mintz, Hideo Takebayashi, George Dangas, Issam Moussa, Roxana Mehran, Alexandra J. Lansky, Edward Kreps, Michael Collins, Antonio Colombo, Gregg W. Stone, Martin B. Leon, Jeffrey W. Moses

Research output: Contribution to journalArticlepeer-review

Abstract

Background - It is not clear why some plaque ruptures lead to acute coronary syndromes (ACS) but others do not. Methods and Results - We analyzed 80 plaque ruptures in 74 patients and compared culprit lesions of ACS patients with nonculprit lesions of ACS patients and lesions of non-ACS patients; both culprit and nonculprit plaque ruptures were studied in 6 of 54 ACS patients. Intravascular ultrasound findings suggesting thrombus were observed more frequently in culprit lesions of ACS patients (n=35) compared with nonculprit lesions of ACS patients (n=19) and lesions of non-ACS patients (n=26): 60% versus 32% versus 8% (P2, P

Original languageEnglish
Pages (from-to)2473-2478
Number of pages6
JournalCirculation
Volume108
Issue number20
DOIs
Publication statusPublished - Nov 18 2003

Keywords

  • Atherosclerosis
  • Coronary disease
  • Ultrasonics

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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