TY - JOUR
T1 - Intravenous artesunate reduces parasite clearance time, duration of intensive care, and hospital treatment in patients with severe malaria in Europe
T2 - The TropNet severe malaria study
AU - Kurth, Florian
AU - Develoux, Michel
AU - Mechain, Matthieu
AU - Clerinx, Jan
AU - Antinori, Spinello
AU - Gjørup, Ida E.
AU - Gascon, Joaquím
AU - Mørch, Kristine
AU - Nicastri, Emanuele
AU - Ramharter, Michael
AU - Bartoloni, Alessandro
AU - Visser, Leo
AU - Rolling, Thierry
AU - Zanger, Philipp
AU - Calleri, Guido
AU - Salas-Coronas, Joaquín
AU - Nielsen, Henrik
AU - Just-Nübling, Gudrun
AU - Neumayr, Andreas
AU - Hachfeld, Anna
AU - Schmid, Matthias L.
AU - Antonini, Pietro
AU - Pongratz, Peter
AU - Kern, Peter
AU - Saraiva Da Cunha, José
AU - Soriano-Arandes, Antoni
AU - Schunk, Mirjam
AU - Suttorp, Norbert
AU - Hatz, Christoph
AU - Zoller, Thomas
PY - 2015/11/1
Y1 - 2015/11/1
N2 - Intravenous artesunate improves survival in severe malaria, but clinical trial data from nonendemic countries are scarce. The TropNet severe malaria database was analyzed to compare outcomes of artesunate vs quinine treatment. Artesunate reduced parasite clearance time and duration of intensive care unit and hospital treatment in European patients with imported severe malaria.
AB - Intravenous artesunate improves survival in severe malaria, but clinical trial data from nonendemic countries are scarce. The TropNet severe malaria database was analyzed to compare outcomes of artesunate vs quinine treatment. Artesunate reduced parasite clearance time and duration of intensive care unit and hospital treatment in European patients with imported severe malaria.
KW - artesunate
KW - clinical study
KW - Plasmodium falciparum
KW - quinine
KW - severe malaria
UR - http://www.scopus.com/inward/record.url?scp=84946721569&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84946721569&partnerID=8YFLogxK
U2 - 10.1093/cid/civ575
DO - 10.1093/cid/civ575
M3 - Article
C2 - 26187021
AN - SCOPUS:84946721569
VL - 61
SP - 1441
EP - 1444
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
SN - 1058-4838
IS - 9
ER -