Intravenous gammaglobulin therapy for chronic idiopathic thrombocytopenic purpura in adults

S. C. Rizzo, G. Grignani, G. Gamba, G. Bedarida, F. D'Agostino

Research output: Contribution to journalArticle

Abstract

The possibility of treating chronic ITP in adults with monomeric IgG is investigated. A platelet rise was observed in all treated subjects although the height of the peak was quite variable. A platelet count of ≥50 x 109/l was observed in 11 out of 14 patients. Splenectomized subjects responded well to the treatment. The therapeutic effect is in general short-lived. No significant side-effects were observed. Circulating immune complexes appeared or increased after the infusion of high doses of this immunoglobulin.

Original languageEnglish
Pages (from-to)337-340
Number of pages4
JournalHaematologica
Volume70
Issue number4
Publication statusPublished - 1985

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Inosine Triphosphate
Idiopathic Thrombocytopenic Purpura
Therapeutic Uses
Antigen-Antibody Complex
Platelet Count
Immunoglobulins
Blood Platelets
Immunoglobulin G
Therapeutics

ASJC Scopus subject areas

  • Hematology

Cite this

Rizzo, S. C., Grignani, G., Gamba, G., Bedarida, G., & D'Agostino, F. (1985). Intravenous gammaglobulin therapy for chronic idiopathic thrombocytopenic purpura in adults. Haematologica, 70(4), 337-340.

Intravenous gammaglobulin therapy for chronic idiopathic thrombocytopenic purpura in adults. / Rizzo, S. C.; Grignani, G.; Gamba, G.; Bedarida, G.; D'Agostino, F.

In: Haematologica, Vol. 70, No. 4, 1985, p. 337-340.

Research output: Contribution to journalArticle

Rizzo, SC, Grignani, G, Gamba, G, Bedarida, G & D'Agostino, F 1985, 'Intravenous gammaglobulin therapy for chronic idiopathic thrombocytopenic purpura in adults', Haematologica, vol. 70, no. 4, pp. 337-340.
Rizzo SC, Grignani G, Gamba G, Bedarida G, D'Agostino F. Intravenous gammaglobulin therapy for chronic idiopathic thrombocytopenic purpura in adults. Haematologica. 1985;70(4):337-340.
Rizzo, S. C. ; Grignani, G. ; Gamba, G. ; Bedarida, G. ; D'Agostino, F. / Intravenous gammaglobulin therapy for chronic idiopathic thrombocytopenic purpura in adults. In: Haematologica. 1985 ; Vol. 70, No. 4. pp. 337-340.
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