Intravenous gammaglobulin therapy for chronic idiopathic thrombocytopenic purpura in adults

S. C. Rizzo; G. Grignani; G. Gamba; G. Bedarida; F. D'Agostino

Intravenous gammaglobulin therapy for chronic idiopathic thrombocytopenic purpura in adults

S. C. Rizzo, G. Grignani, G. Gamba, G. Bedarida, F. D'Agostino

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

The possibility of treating chronic ITP in adults with monomeric IgG is investigated. A platelet rise was observed in all treated subjects although the height of the peak was quite variable. A platelet count of ≥50 x 10⁹/l was observed in 11 out of 14 patients. Splenectomized subjects responded well to the treatment. The therapeutic effect is in general short-lived. No significant side-effects were observed. Circulating immune complexes appeared or increased after the infusion of high doses of this immunoglobulin.

Original language	English
Pages (from-to)	337-340
Number of pages	4
Journal	Haematologica
Volume	70
Issue number	4
Publication status	Published - 1985

ASJC Scopus subject areas

Hematology

Cite this

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title = "Intravenous gammaglobulin therapy for chronic idiopathic thrombocytopenic purpura in adults",

abstract = "The possibility of treating chronic ITP in adults with monomeric IgG is investigated. A platelet rise was observed in all treated subjects although the height of the peak was quite variable. A platelet count of ≥50 x 109/l was observed in 11 out of 14 patients. Splenectomized subjects responded well to the treatment. The therapeutic effect is in general short-lived. No significant side-effects were observed. Circulating immune complexes appeared or increased after the infusion of high doses of this immunoglobulin.",

author = "Rizzo, {S. C.} and G. Grignani and G. Gamba and G. Bedarida and F. D'Agostino",

year = "1985",

language = "English",

volume = "70",

pages = "337--340",

journal = "Haematologica",

issn = "0390-6078",

publisher = "NLM (Medline)",

number = "4",

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TY - JOUR

T1 - Intravenous gammaglobulin therapy for chronic idiopathic thrombocytopenic purpura in adults

AU - Rizzo, S. C.

AU - Grignani, G.

AU - Gamba, G.

AU - Bedarida, G.

AU - D'Agostino, F.

PY - 1985

Y1 - 1985

N2 - The possibility of treating chronic ITP in adults with monomeric IgG is investigated. A platelet rise was observed in all treated subjects although the height of the peak was quite variable. A platelet count of ≥50 x 109/l was observed in 11 out of 14 patients. Splenectomized subjects responded well to the treatment. The therapeutic effect is in general short-lived. No significant side-effects were observed. Circulating immune complexes appeared or increased after the infusion of high doses of this immunoglobulin.

AB - The possibility of treating chronic ITP in adults with monomeric IgG is investigated. A platelet rise was observed in all treated subjects although the height of the peak was quite variable. A platelet count of ≥50 x 109/l was observed in 11 out of 14 patients. Splenectomized subjects responded well to the treatment. The therapeutic effect is in general short-lived. No significant side-effects were observed. Circulating immune complexes appeared or increased after the infusion of high doses of this immunoglobulin.

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M3 - Article

C2 - 3935533

AN - SCOPUS:0022408324

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JO - Haematologica

JF - Haematologica

SN - 0390-6078

IS - 4

ER -

Intravenous gammaglobulin therapy for chronic idiopathic thrombocytopenic purpura in adults

Abstract

ASJC Scopus subject areas

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