Intravenous gammaglobulin therapy for chronic idiopathic thrombocytopenic purpura in adults

S. C. Rizzo, G. Grignani, G. Gamba, G. Bedarida, F. D'Agostino

Research output: Contribution to journalArticle

Abstract

The possibility of treating chronic ITP in adults with monomeric IgG is investigated. A platelet rise was observed in all treated subjects although the height of the peak was quite variable. A platelet count of ≥50 x 109/l was observed in 11 out of 14 patients. Splenectomized subjects responded well to the treatment. The therapeutic effect is in general short-lived. No significant side-effects were observed. Circulating immune complexes appeared or increased after the infusion of high doses of this immunoglobulin.

Original languageEnglish
Pages (from-to)337-340
Number of pages4
JournalHaematologica
Volume70
Issue number4
Publication statusPublished - 1985

ASJC Scopus subject areas

  • Hematology

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