TY - JOUR
T1 - Intravenous methylprednisolone pulse therapy for children with epileptic encephalopathy
AU - Pera, Maria Carmela
AU - Randazzo, Giovanna
AU - Masnada, Silvia
AU - Dontin, Serena Donetti
AU - De Giorgis, Valentina
AU - Balottin, Umberto
AU - Veggiotti, Pierangelo
PY - 2015/7/1
Y1 - 2015/7/1
N2 - The aim of this retrospective study of children affected by epileptic encephalopathy was to evaluate seizure frequency, electroencephalographic pattern and neuropsychological status, before and after intravenous methylprednisolone therapy. Eleven children with epileptic encephalopathy were administered one cycle of intravenous methylprednisolone (15-30 mg/kg/day for three consecutive days, once a month for four months) in addition to constant dosages of their regular antiepileptic drugs. The treatment resulted in statistically significant reductions of generalized slow spike-and-wave discharges (p
AB - The aim of this retrospective study of children affected by epileptic encephalopathy was to evaluate seizure frequency, electroencephalographic pattern and neuropsychological status, before and after intravenous methylprednisolone therapy. Eleven children with epileptic encephalopathy were administered one cycle of intravenous methylprednisolone (15-30 mg/kg/day for three consecutive days, once a month for four months) in addition to constant dosages of their regular antiepileptic drugs. The treatment resulted in statistically significant reductions of generalized slow spike-and-wave discharges (p
KW - Epileptic encephalopathy
KW - Intravenous methylprednisolone
KW - Refractory epilepsy
UR - http://www.scopus.com/inward/record.url?scp=84944450040&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84944450040&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:84944450040
VL - 30
SP - 173
EP - 179
JO - Functional Neurology
JF - Functional Neurology
SN - 0393-5264
IS - 3
ER -