Anestetici endovenosi versus inalatori nell'anestesia per il prelievo di midollo osseo a scopo di trapianto.

Translated title of the contribution: Intravenous versus inhalation anesthetics in anesthesia for bone marrow harvest for transplantation

E. Domenegati, M. Bonfichi, P. Filisetti, F. Reali, C. Reposi, R. Ciccone

Research output: Contribution to journalArticlepeer-review

Abstract

It is well known that nitrous oxide and many volatile anaesthetic drugs possess a certain degree of myelodepressive activity. The authors' aim has been to evaluate the degree of proliferative activity after exposure to forane or propofol. Bone marrow samples have been cultured after general anaesthesia induced and maintained by the same agents; cultures have also been performed after samples exposure to forane and propofol. The results have not shown significative differences in the haemopoietic colonies growth of bone marrow harvested from patients underwent intravenous or inhalatory anaesthesia. In vitro study has shown a significative variation of the colonies growth at the forane higher concentration. Intravenous anaesthetic may be safer for bone marrow harvest for transplantation.

Translated title of the contributionIntravenous versus inhalation anesthetics in anesthesia for bone marrow harvest for transplantation
Original languageItalian
Pages (from-to)157-161
Number of pages5
JournalMinerva Anestesiologica
Volume59
Issue number4
Publication statusPublished - Apr 1993

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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