Intraventricular interferon in a case of subacute sclerosing panencephalitis

A. Boiardi, S. M. Baldini, A. Sghirlanzoni, R. Mancuso, F. Corridori

Research output: Contribution to journalArticlepeer-review


a patient with subacute sclerosing panencephalitis (SSPE) was treated by direct administration of Interferon B into the cerebral ventricles. Immediately after the first dose intrathecal synthesis of IgG and the CNS antimeasles antibody titer fell significantly, only to rise again to the pretreatment levels 2 months after discontinuation of treatment. There was no improvement in the patient's clinical status.

Original languageEnglish
Pages (from-to)277-281
Number of pages5
JournalItalian Journal of Neurological Sciences
Issue number3
Publication statusPublished - Jun 1987


  • Interferon B
  • intraventricular administration
  • SSPE

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


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