Intraventricular interferon in a case of subacute sclerosing panencephalitis

A. Boiardi; S. M. Baldini; A. Sghirlanzoni; R. Mancuso; F. Corridori

doi:10.1007/BF02337487

Intraventricular interferon in a case of subacute sclerosing panencephalitis

A. Boiardi, S. M. Baldini, A. Sghirlanzoni, R. Mancuso, F. Corridori

Fondazione Don Carlo Gnocchi Onlus

Research output: Contribution to journal › Article › peer-review

Abstract

a patient with subacute sclerosing panencephalitis (SSPE) was treated by direct administration of Interferon B into the cerebral ventricles. Immediately after the first dose intrathecal synthesis of IgG and the CNS antimeasles antibody titer fell significantly, only to rise again to the pretreatment levels 2 months after discontinuation of treatment. There was no improvement in the patient's clinical status.

Original language	English
Pages (from-to)	277-281
Number of pages	5
Journal	Italian Journal of Neurological Sciences
Volume	8
Issue number	3
DOIs	https://doi.org/10.1007/BF02337487
Publication status	Published - Jun 1987

Keywords

Interferon B
intraventricular administration
SSPE

ASJC Scopus subject areas

Neuroscience(all)
Clinical Neurology

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10.1007/BF02337487

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abstract = "a patient with subacute sclerosing panencephalitis (SSPE) was treated by direct administration of Interferon B into the cerebral ventricles. Immediately after the first dose intrathecal synthesis of IgG and the CNS antimeasles antibody titer fell significantly, only to rise again to the pretreatment levels 2 months after discontinuation of treatment. There was no improvement in the patient's clinical status.",

keywords = "Interferon B, intraventricular administration, SSPE",

author = "A. Boiardi and Baldini, {S. M.} and A. Sghirlanzoni and R. Mancuso and F. Corridori",

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AU - Boiardi, A.

AU - Baldini, S. M.

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AU - Mancuso, R.

AU - Corridori, F.

PY - 1987/6

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N2 - a patient with subacute sclerosing panencephalitis (SSPE) was treated by direct administration of Interferon B into the cerebral ventricles. Immediately after the first dose intrathecal synthesis of IgG and the CNS antimeasles antibody titer fell significantly, only to rise again to the pretreatment levels 2 months after discontinuation of treatment. There was no improvement in the patient's clinical status.

AB - a patient with subacute sclerosing panencephalitis (SSPE) was treated by direct administration of Interferon B into the cerebral ventricles. Immediately after the first dose intrathecal synthesis of IgG and the CNS antimeasles antibody titer fell significantly, only to rise again to the pretreatment levels 2 months after discontinuation of treatment. There was no improvement in the patient's clinical status.

KW - Interferon B

KW - intraventricular administration

KW - SSPE

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Intraventricular interferon in a case of subacute sclerosing panencephalitis

Abstract

Keywords

ASJC Scopus subject areas

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