Intravitreal Ranibizumab for myopic choroidal neovascularization after pars plana vitrectomy and silicone oil tamponade

Maria Lucia Cascavilla, Giuseppe Querques, Lea Querques, Marco Codenotti, Francesco Bandello

Research output: Contribution to journalArticle

Abstract

To report on intravitreal Ranibizumab for intervening myopic choroidal neovascularization (CNV) in a case of retinal detachment successfully repaired with pars plana vitrectomy and silicone oil tamponade. Methods: Intravitreal ranibizumab was performed in a 67-year-old woman with CNV complicating pathologic myopia. The patient had previously undergone vitrectomy and silicone oil tamponade for retinal detachment. Results: At 2 months from intravitreal ranibizumab, best-corrected visual acuity (BCVA) improved from count fingers to 20/100, and intraocular pressure (IOP) was 16 mm Hg. Fluorescein angiography (FA) and spectral-domain optical coherence tomography (SD-OCT) showed resolution of late leakage and subretinal/intraretinal fluid, respectively. Conclusions: Administration of intravitreal anti-VEGF in patients with silicone oil as intraocular tamponade may represent an intriguing treatment option. Our results suggest that intravitreal injections of Ranibizumab may lead to a rapid improvement in both functional (BCVA) and morphologic (FA and SD-OCT) parameters of CNV activity, without significant rise in IOP, in eyes with silicone oil as intraocular tamponade.

Original languageEnglish
Pages (from-to)913-916
Number of pages4
JournalEuropean Journal of Ophthalmology
Volume23
Issue number6
DOIs
Publication statusPublished - Jun 23 2013

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Keywords

  • Anti-vascular endothelial growth factor
  • Choroidal neovascularization
  • Pars plana vitrectomy
  • Pathologic myopia
  • PDMS
  • Ranibizumab
  • Silicone oil

ASJC Scopus subject areas

  • Ophthalmology
  • Medicine(all)

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