Abstract
The term "invisible dermatoses" is often used in two different contexts: 1) dermatoses which are invisible to the clinician, i.e., diseases with no significant clinical features; 2) dermatoses which are invisible to the pathologist. These latter comprise a wide spectrum of entities which present with definite and obvious clinical features, but subtle or hidden histological features and are therefore "invisible" histologically. Diagnosis of such diseases represents a great challenge to both the dermatologist and dermatopathologist. The list of such diseases, originally comprising only few entities, has been gradually expanded over decades and now is a large one. This review focuses on the recently expanded spectrum of such diseases, and offers to the dermatopathologist a strategy for their diagnosis, based mainly on proper awareness, recognition of subtle features, special stains, special investigations such as immunofluorescence and histochemistry and proper clinicopathological correlation.
Original language | English |
---|---|
Pages (from-to) | 500-515 |
Number of pages | 16 |
Journal | Giornale Italiano di Dermatologia e Venereologia |
Volume | 152 |
Issue number | 5 |
DOIs | |
Publication status | Published - Oct 1 2017 |
Externally published | Yes |
Keywords
- Diagnosis
- Hemosiderosis
- Hydroxyurea
- Pathology
- Skin diseases
ASJC Scopus subject areas
- Dermatology