Abstract
The term "invisible dermatoses" is often used in two different contexts: 1) dermatoses which are invisible to the clinician, i.e., diseases with no significant clinical features; 2) dermatoses which are invisible to the pathologist. These latter comprise a wide spectrum of entities which present with definite and obvious clinical features, but subtle or hidden histological features and are therefore "invisible" histologically. Diagnosis of such diseases represents a great challenge to both the dermatologist and dermatopathologist. The list of such diseases, originally comprising only few entities, has been gradually expanded over decades and now is a large one. This review focuses on the recently expanded spectrum of such diseases, and offers to the dermatopathologist a strategy for their diagnosis, based mainly on proper awareness, recognition of subtle features, special stains, special investigations such as immunofluorescence and histochemistry and proper clinicopathological correlation.
| Original language | English |
|---|---|
| Pages (from-to) | 500-515 |
| Number of pages | 16 |
| Journal | Giornale Italiano di Dermatologia e Venereologia |
| Volume | 152 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Oct 1 2017 |
| Externally published | Yes |
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Keywords
- Diagnosis
- Hemosiderosis
- Hydroxyurea
- Pathology
- Skin diseases
ASJC Scopus subject areas
- Dermatology
Cite this
Invisible dermatoses from the perspective of the dermatopathologist : New observations. / Tomasini, Carlo.
In: Giornale Italiano di Dermatologia e Venereologia, Vol. 152, No. 5, 01.10.2017, p. 500-515.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Invisible dermatoses from the perspective of the dermatopathologist
T2 - New observations
AU - Tomasini, Carlo
PY - 2017/10/1
Y1 - 2017/10/1
N2 - The term "invisible dermatoses" is often used in two different contexts: 1) dermatoses which are invisible to the clinician, i.e., diseases with no significant clinical features; 2) dermatoses which are invisible to the pathologist. These latter comprise a wide spectrum of entities which present with definite and obvious clinical features, but subtle or hidden histological features and are therefore "invisible" histologically. Diagnosis of such diseases represents a great challenge to both the dermatologist and dermatopathologist. The list of such diseases, originally comprising only few entities, has been gradually expanded over decades and now is a large one. This review focuses on the recently expanded spectrum of such diseases, and offers to the dermatopathologist a strategy for their diagnosis, based mainly on proper awareness, recognition of subtle features, special stains, special investigations such as immunofluorescence and histochemistry and proper clinicopathological correlation.
AB - The term "invisible dermatoses" is often used in two different contexts: 1) dermatoses which are invisible to the clinician, i.e., diseases with no significant clinical features; 2) dermatoses which are invisible to the pathologist. These latter comprise a wide spectrum of entities which present with definite and obvious clinical features, but subtle or hidden histological features and are therefore "invisible" histologically. Diagnosis of such diseases represents a great challenge to both the dermatologist and dermatopathologist. The list of such diseases, originally comprising only few entities, has been gradually expanded over decades and now is a large one. This review focuses on the recently expanded spectrum of such diseases, and offers to the dermatopathologist a strategy for their diagnosis, based mainly on proper awareness, recognition of subtle features, special stains, special investigations such as immunofluorescence and histochemistry and proper clinicopathological correlation.
KW - Diagnosis
KW - Hemosiderosis
KW - Hydroxyurea
KW - Pathology
KW - Skin diseases
UR - http://www.scopus.com/inward/record.url?scp=85029395120&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85029395120&partnerID=8YFLogxK
U2 - 10.23736/S0392-0488.17.05720-0
DO - 10.23736/S0392-0488.17.05720-0
M3 - Review article
VL - 152
SP - 500
EP - 515
JO - Minerva dermatologica
JF - Minerva dermatologica
SN - 0392-0488
IS - 5
ER -