Involuntary movements after correction of vitamin B12 deficiency: A video-case report

Caterina Zanus, Elena Alberini, Paola Costa, Franco Colonna, Floriana Zennaro, Marco Carrozzi

Research output: Contribution to journalArticlepeer-review


Involuntary movements can appear before and after initiation of vitamin B12 treatment. The pathogenesis of involuntary movements in vitamin B12 deficiency and their relationship with cobalamin injection remain unclear due to a lack of video-EEG documentation making the electroclinical correlation difficult to ascertain. Here, we report video-EEG and neuroimaging findings of an 11-month-old girl with vitamin B12 deficiency, who acutely developed involuntary movements a few days after initiation of vitamin B12 treatment with normal vitamin plasmatic levels. Abnormal movements were a combination of tremor and myoclonus involving the face, mouth, and left arm, which disappeared after discontinuation of therapy.

Original languageEnglish
Pages (from-to)174-180
Number of pages7
JournalEpileptic Disorders
Issue number2
Publication statusPublished - Jun 2012


  • Encephalopathy
  • Involuntary movements
  • Video-EEG
  • Vitamin B12 deficiency (vB12 deficiency)

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology


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