TY - JOUR
T1 - Iopamidol in cardioangiography
T2 - a retrospective, multicenter study - Part I. Adult patients
AU - Ballerini, Luigi
AU - Barbaresi, Franco
AU - Binaghi, Giovanni
AU - Cernigliaro, Carmelo
AU - Chioin, Raffaello
AU - Fattori, Rosella
AU - Inglese, Luigi
AU - Invernizzi, Giorgio
AU - di Priolo, Susanna Leto
AU - Passoni, Federico
AU - Richichi, Giuseppe
AU - Squarcia, Umberto
AU - Violini, Roberta
PY - 1992/3
Y1 - 1992/3
N2 - To evaluate the occurrence of complications during diagnostic or interventional catheterization a retrospective analysis of catheterization procedures in 1.2 italian laboratories using the nonionic contrast medium (CM) iopamidol (370mgI/ml) was performed. Data obtained on 26,219 patients ≥ 14 years are presented. The overall complication rate was 1.89% (485/26,219). The overall mortality rate was 0.1% (27/26,219). Procedure related complications were 389 (1.48%) and CM related complications were 106 (0.4%). No death was attributed to CM. Ventricular fibrillation (VF) rate was 0.11% comparable to the low rate observed with nonionic CM in other studies and less than the rate observed in surveys concerning the use of ionic CM. Fifty-seven thrombotic events were recorded (0.22%), a rate comparable with other surveys with ionic and nonionic CM. The total complication rate (6.1%), the rates of coronary occlusion (1.34%), myocardial infarction (0.37%) and urgent coronary artery by-pass grafting (0.5%) in 1,348 coronary angioplasties were lower than those recorded in previous surveys. These data confirm a good tolerability and no increased risk of VF and thrombotic events with iopamidol in cardiac catheterization.
AB - To evaluate the occurrence of complications during diagnostic or interventional catheterization a retrospective analysis of catheterization procedures in 1.2 italian laboratories using the nonionic contrast medium (CM) iopamidol (370mgI/ml) was performed. Data obtained on 26,219 patients ≥ 14 years are presented. The overall complication rate was 1.89% (485/26,219). The overall mortality rate was 0.1% (27/26,219). Procedure related complications were 389 (1.48%) and CM related complications were 106 (0.4%). No death was attributed to CM. Ventricular fibrillation (VF) rate was 0.11% comparable to the low rate observed with nonionic CM in other studies and less than the rate observed in surveys concerning the use of ionic CM. Fifty-seven thrombotic events were recorded (0.22%), a rate comparable with other surveys with ionic and nonionic CM. The total complication rate (6.1%), the rates of coronary occlusion (1.34%), myocardial infarction (0.37%) and urgent coronary artery by-pass grafting (0.5%) in 1,348 coronary angioplasties were lower than those recorded in previous surveys. These data confirm a good tolerability and no increased risk of VF and thrombotic events with iopamidol in cardiac catheterization.
KW - cardiac catheterization
KW - complications
KW - iopamidol
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U2 - 10.1007/BF01137564
DO - 10.1007/BF01137564
M3 - Article
C2 - 1619303
AN - SCOPUS:0026684754
VL - 8
SP - 35
EP - 43
JO - International Journal of Cardiovascular Imaging
JF - International Journal of Cardiovascular Imaging
SN - 1569-5794
IS - 1
ER -