Iopamidol in cardioangiography: a retrospective, multicenter study - Part I. Adult patients

Luigi Ballerini, Franco Barbaresi, Giovanni Binaghi, Carmelo Cernigliaro, Raffaello Chioin, Rosella Fattori, Luigi Inglese, Giorgio Invernizzi, Susanna Leto di Priolo, Federico Passoni, Giuseppe Richichi, Umberto Squarcia, Roberta Violini

Research output: Contribution to journalArticle

Abstract

To evaluate the occurrence of complications during diagnostic or interventional catheterization a retrospective analysis of catheterization procedures in 1.2 italian laboratories using the nonionic contrast medium (CM) iopamidol (370mgI/ml) was performed. Data obtained on 26,219 patients ≥ 14 years are presented. The overall complication rate was 1.89% (485/26,219). The overall mortality rate was 0.1% (27/26,219). Procedure related complications were 389 (1.48%) and CM related complications were 106 (0.4%). No death was attributed to CM. Ventricular fibrillation (VF) rate was 0.11% comparable to the low rate observed with nonionic CM in other studies and less than the rate observed in surveys concerning the use of ionic CM. Fifty-seven thrombotic events were recorded (0.22%), a rate comparable with other surveys with ionic and nonionic CM. The total complication rate (6.1%), the rates of coronary occlusion (1.34%), myocardial infarction (0.37%) and urgent coronary artery by-pass grafting (0.5%) in 1,348 coronary angioplasties were lower than those recorded in previous surveys. These data confirm a good tolerability and no increased risk of VF and thrombotic events with iopamidol in cardiac catheterization.

Original languageEnglish
Pages (from-to)35-43
Number of pages9
JournalThe International Journal of Cardiac Imaging
Volume8
Issue number1
DOIs
Publication statusPublished - Mar 1992

Keywords

  • cardiac catheterization
  • complications
  • iopamidol

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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