TY - JOUR
T1 - Iron deficiency
T2 - An ominous sign in patients with systolic chronic heart failure
AU - Jankowska, Ewa A.
AU - Rozentryt, Piotr
AU - Witkowska, Agnieszka
AU - Nowak, Jolanta
AU - Hartmann, Oliver
AU - Ponikowska, Beata
AU - Borodulin-Nadzieja, Ludmila
AU - Banasiak, Waldemar
AU - Polonski, Lech
AU - Filippatos, Gerasimos
AU - McMurray, John J V
AU - Anker, Stefan D.
AU - Ponikowski, Piotr
PY - 2010/8
Y1 - 2010/8
N2 - Aims Beyond erythropoiesis, iron is involved in numerous biological processes crucial for maintenance of homeostasis. Patients with chronic heart failure (CHF) are prone to develop iron deficiency (ID), and iron supplementation improves their functional status and quality of life. We sought to examine the relationship between ID and survival in patients with systolic CHF. Methods and resultsIn a prospective observational study, we evaluated 546 patients with stable systolic CHF [age: 55 ± 11 (mean ± standard deviation) years, males: 88, left ventricular ejection fraction: 26 ± 7, New York Heart Association (NYHA) class (I/II/III/IV): 57/221/226/42]. Iron deficiency was defined as: ferritin
AB - Aims Beyond erythropoiesis, iron is involved in numerous biological processes crucial for maintenance of homeostasis. Patients with chronic heart failure (CHF) are prone to develop iron deficiency (ID), and iron supplementation improves their functional status and quality of life. We sought to examine the relationship between ID and survival in patients with systolic CHF. Methods and resultsIn a prospective observational study, we evaluated 546 patients with stable systolic CHF [age: 55 ± 11 (mean ± standard deviation) years, males: 88, left ventricular ejection fraction: 26 ± 7, New York Heart Association (NYHA) class (I/II/III/IV): 57/221/226/42]. Iron deficiency was defined as: ferritin
KW - Chronic heart failure
KW - Iron deficiency
KW - Survival
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U2 - 10.1093/eurheartj/ehq158
DO - 10.1093/eurheartj/ehq158
M3 - Article
C2 - 20570952
AN - SCOPUS:77955453008
VL - 31
SP - 1872
EP - 1880
JO - European Heart Journal
JF - European Heart Journal
SN - 0195-668X
IS - 15
ER -