Iron influences on the Gut-Brain axis and development of type 2 diabetes

José Manuel Fernández Real, José Maria Moreno-Navarrete, Melania Manco

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: Microbiota/neuroendocrine interactions with health and disease are increasingly recognized. Main Body: Aging is associated with progressive iron storage and development of type 2 diabetes, which impacts on brain microstructure and function, mainly in obese subjects. Iron status is also mutually influencing the composition of the gut microbiota, which in turn may affect cognition through the gut-brain axis. Short Conclusion: In this article we update the possible role of iron in all these interactions.

Original languageEnglish
Pages (from-to)443-449
Number of pages7
JournalCritical Reviews in Food Science and Nutrition
Volume59
Issue number3
DOIs
Publication statusPublished - 2019

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