Abstract
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe, rare, and life-threatening adverse reactions to medications. Their incidence is approximately two patients per million population per year. Several cases have been reported in the literature in which SJS and TEN have occurred in patients with a neoplasm undergoing radiation therapy and who are taking an anticonvulsant. We report a case of SJS-TEN that developed in a 51-year-old woman with nonresectable non-small-cell lung cancer during treatment with phenobarbital plus radiation therapy for bone metastases but in whom the irradiated areas did not exhibit the SJS skin reaction. To our knowledge, no similar cases have been reported in the literature.
| Original language | English |
|---|---|
| Pages (from-to) | 103-106 |
| Number of pages | 4 |
| Journal | Japanese Journal of Radiology |
| Volume | 27 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Feb 2009 |
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Keywords
- Phenobarbital
- Radiotherapy
- Skin reaction
- Spared fields
- Stevens-Johnson syndrome
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
Irradiated fields spared Stevens-Johnson syndrome in a patient undergoing radiotherapy for bone metastases. / Musio, Daniela; Parisi, Elisabetta; Dionisi, Francesco; Parisi, Giuseppe; Caiazzo, Rossella; Bulzonetti, Nadia; Lichtner, Miriam; Raffetto, Nicola; Vullo, Vincenzo; Banelli, Enzo.
In: Japanese Journal of Radiology, Vol. 27, No. 2, 02.2009, p. 103-106.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Irradiated fields spared Stevens-Johnson syndrome in a patient undergoing radiotherapy for bone metastases
AU - Musio, Daniela
AU - Parisi, Elisabetta
AU - Dionisi, Francesco
AU - Parisi, Giuseppe
AU - Caiazzo, Rossella
AU - Bulzonetti, Nadia
AU - Lichtner, Miriam
AU - Raffetto, Nicola
AU - Vullo, Vincenzo
AU - Banelli, Enzo
PY - 2009/2
Y1 - 2009/2
N2 - Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe, rare, and life-threatening adverse reactions to medications. Their incidence is approximately two patients per million population per year. Several cases have been reported in the literature in which SJS and TEN have occurred in patients with a neoplasm undergoing radiation therapy and who are taking an anticonvulsant. We report a case of SJS-TEN that developed in a 51-year-old woman with nonresectable non-small-cell lung cancer during treatment with phenobarbital plus radiation therapy for bone metastases but in whom the irradiated areas did not exhibit the SJS skin reaction. To our knowledge, no similar cases have been reported in the literature.
AB - Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe, rare, and life-threatening adverse reactions to medications. Their incidence is approximately two patients per million population per year. Several cases have been reported in the literature in which SJS and TEN have occurred in patients with a neoplasm undergoing radiation therapy and who are taking an anticonvulsant. We report a case of SJS-TEN that developed in a 51-year-old woman with nonresectable non-small-cell lung cancer during treatment with phenobarbital plus radiation therapy for bone metastases but in whom the irradiated areas did not exhibit the SJS skin reaction. To our knowledge, no similar cases have been reported in the literature.
KW - Phenobarbital
KW - Radiotherapy
KW - Skin reaction
KW - Spared fields
KW - Stevens-Johnson syndrome
UR - http://www.scopus.com/inward/record.url?scp=65149096382&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=65149096382&partnerID=8YFLogxK
U2 - 10.1007/s11604-008-0297-9
DO - 10.1007/s11604-008-0297-9
M3 - Article
VL - 27
SP - 103
EP - 106
JO - Japanese Journal of Radiology
JF - Japanese Journal of Radiology
SN - 1867-1071
IS - 2
ER -