Irrigated-tip magnetic catheter ablation of AF: A long-term prospective study in 130 patients

Carlo Pappone, Gabriele Vicedomini, Enrico Frigoli, Luigi Giannelli, Cristiano Ciaccio, Mario Baldi, Francesca Zuffada, Massimo Saviano, Alessia Pappone, Simonetta Cris, Andrea Petretta, Vincenzo Santinelli

Research output: Contribution to journalArticlepeer-review

Abstract

Background Nonirrigated magnetic ablation may result in potential char, ineffective lesions, and longer procedure times. Objective This study sought to report the safety and long-term efficacy of irrigated-tip magnetic ablation of atrial fibrillation (AF). Methods Catheter ablation was remotely performed using a new irrigated-tip magnetic catheter (ThermoCool NaviStar-RMT, Biosense Webster, Diamond Bar, CA) in 130 consecutive patients (mean age 59.7 ± 10.5 years) with symptomatic paroxysmal (81 patients) or persistent (49 patients) AF. The radiofrequency (RF) generator was set to fixed power of 30 W. The primary end point of the study was freedom from atrial tachycardia (AT)/AF off antiarrhythmic drugs. Results The procedure was safely performed in all conventional ablation targets, but crossover to manual catheters was required in 12 patients to complete the mitral isthmus line. The total procedure time was 94.6 ± 15.3 minutes. Impedance values significantly decreased during RF applications (P <.001) and the maximum temperature on the catheter tip was 36.4°C ± 0.8°C. The follow-up duration was 15.3 ± 4.9 months. The primary end point was achieved in 66 of 81(81.4%) patients with paroxysmal AF and in 33 of 49 (67.3%) with persistent AF (P = .035, by log-rank test). Patients with paroxysmal AF had higher late AF recurrence (P =.044). Overall, postablation incessant left AT developed in 7 of 130 (5.4%) patients. Major complications were not observed. Left atrial diameter (P <.001) and heart failure (P = .032) predicted arrhythmia recurrence after remote irrigated-tip ablation. Conclusion Remote ablation with irrigated-tip magnetic catheters can be safely and effectively performed in patients with AF, but longer follow-up periods are required to evaluate late AF recurrences.

Original languageEnglish
Pages (from-to)8-15
Number of pages8
JournalHeart Rhythm
Volume8
Issue number1
DOIs
Publication statusPublished - Jan 2011

Keywords

  • Atrial fibrillation
  • Catheter ablation
  • Irrigated radiofrequency ablation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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